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dc.contributor.authorPicão, Renata Cristina [UNIFESP]
dc.contributor.authorPoirel, Laurent
dc.contributor.authorDemarta, Antonella
dc.contributor.authorFerreira Silva, Carla Sofia
dc.contributor.authorRita Corvaglia, Anna
dc.contributor.authorPetrini, Orlando
dc.contributor.authorNordmann, Patrice
dc.identifier.citationJournal of Antimicrobial Chemotherapy. Oxford: Oxford Univ Press, v. 62, n. 5, p. 948-950, 2008.
dc.description.abstractObjectives: To search for plasmid-mediated qnr genes among waterborne environmental Aeromonas spp. recovered from Switzerland.Methods: Isolates presenting MICs of nalidixic acid or ciprofloxacin >= 1 mg/L were screened for qnr genes by a multiplex PCR approach followed by sequencing. Plasmids were transferred by transformation, and further analysis of the genetic structures surrounding the qnrS2 gene was carried out by PCR and sequencing.Results: A qnrS2 gene was identified from a single Aeromonas allosaccharophila isolate (Lugano lake, Lugano), as part of a mobile insertion cassette located on a broad host range IncU-type plasmid. This plasmid co-harboured a class 1 integron containing the aac(6 ')-Ib-cr, bla(OXA-1), catB3 and arr-3 gene cassettes.Conclusions: These findings strengthen further the role of Aeromonas spp. as a reservoir of antimicrobial resistance determinants in the environment.en
dc.description.sponsorshipMinistere de l'Education Nationale et de la Recherche
dc.description.sponsorshipUniversite Paris XI, France
dc.description.sponsorshipSwiss National Science Foundation
dc.description.sponsorshipNational Research Program 'Antibiotic resistance'
dc.description.sponsorshipEuropean Community
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.publisherOxford Univ Press
dc.relation.ispartofJournal of Antimicrobial Chemotherapy
dc.rightsAcesso aberto
dc.subjectA. allosaccharophilaen
dc.titlePlasmid-mediated quinolone resistance in Aeromonas allosaccharophila recovered from a Swiss lakeen
dc.contributor.institutionHop Bicetre
dc.contributor.institutionUniv Paris Sud
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionIst Cantonale Microbiol
dc.contributor.institutionUniv Geneva
dc.description.affiliationHop Bicetre, AP HP, Serv Bacteriol Virol, INSERM Emerging Resistance Antibiot,U914,Fac Med, K Bicetre, France
dc.description.affiliationUniv Paris Sud, K Bicetre, France
dc.description.affiliationUniversidade Federal de São Paulo, Lab ALERTA, São Paulo, Brazil
dc.description.affiliationIst Cantonale Microbiol, Bellinzona, Switzerland
dc.description.affiliationUniv Geneva, Ctr Med & Univ, Geneva, Switzerland
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Lab ALERTA, São Paulo, Brazil
dc.description.sponsorshipIDMinistere de l'Education Nationale et de la Recherche: UPRES-EA3539
dc.description.sponsorshipIDNational Research Program 'Antibiotic resistance': NRP49
dc.description.sponsorshipIDEuropean Community: DRESP2
dc.description.sponsorshipIDEuropean Community: LSHM-CT-2005-018705
dc.description.sponsorshipIDPDEE: 3682/07-2
dc.description.sourceWeb of Science

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