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dc.contributor.authorTsubone, Camila [UNIFESP]
dc.contributor.authorGarcia, Pedro Lopez [UNIFESP]
dc.contributor.authorGomes, Fabio Pereira [UNIFESP]
dc.contributor.authorMaria Kedor-Hackmann, Erika Rosa [UNIFESP]
dc.contributor.authorRocha Miritello Santoro, Maria Ines [UNIFESP]
dc.identifier.citationAnalytical Letters. Philadelphia: Taylor & Francis Inc, v. 41, n. 3, p. 424-436, 2008.
dc.description.abstractHigh-performance liquid chromatographic (HPLC) and UV derivative spectrophotometric (UVDS) methods were developed and validated for the quantitative determination of nadolol in tablets. the HPLC method was performed on a C18 column with fluorescence detection. the excitation and emission wavelengths were 230 and 300nm, respectively. A mobile phase composed by acetonitrile-water containing 0.1% triethylamine (15:85v/v) and pH adjusted to 4.6 with formic acid was used. the UVDS method was performed taken a signal at 279.5nm. the correlation coefficient (r) obtained for both methods was 0.9999. the proposed methods are simple, precise, accurate, and can be used in routine analysis.en
dc.publisherTaylor & Francis Inc
dc.relation.ispartofAnalytical Letters
dc.rightsAcesso restrito
dc.subjectnadolol tabletsen
dc.subjectUV derivative spectrophotometryen
dc.titleQuantitative determination of nadolol in tablets by high-performance liquid chromatography and UV-derivative spectrophotometryen
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniversidade Federal de São Paulo, Dept Pharm, Fac Pharmaceut Sci, BR-05315970 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Pharm, Fac Pharmaceut Sci, BR-05315970 São Paulo, Brazil
dc.description.sourceWeb of Science

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