Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines

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Data
2007-10-01
Autores
Jacomo, Rafael Henriques
Morais Melo, Raul Antonio
Souto, Fernanda Ribeiro
Mattos, Ederson Roberto de
Oliveira, Claudia Teresa de
Fagundes, Evandro M.
Silva Bittencourt, Henrique Neves da
Bittencourt, Rosane Isabel
Bortolheiro, Teresa Cristina
Paton, Eduardo J. A.
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Carta
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Resumo
We report an increased incidence of high relapse risk features in 157 APL Brazilian patients. Out of 134 patients treated with ATRA and anthracyclines, only 91 (67.9%) achieved remission because 43 (32%) died during induction. the death rate during consolidation was 10.5%. Bleeding complications were the most frequent cause of failure (21.6%).
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Citação
Haematologica-the Hematology Journal. Pavia: Ferrata Storti Foundation, v. 92, n. 10, p. 1431-1432, 2007.