Characteristics of neural and humoral systems involved in the regulation of blood pressure in snakes
Breno, Maria Cristina
Prezoto, Benedito Carlos
Borgheresi, Rosa Anna Maria Barbarulo
Lazari, Maria de Fatima Magalhaes [UNIFESP]
Is part ofComparative Biochemistry and Physiology A-molecular & Integrative Physiology
MetadataShow full item record
Cardiovascular function is affected by many mechanisms, including the autonomic system, the kallikrein-kinin system (KKS), the reninangiotensin system (RAS) and the endothelin system. the function of these systems seems to be fairly well preserved throughout the vertebrate scale, but evolution required several adaptations. Snakes are particularly interesting for studies related to the cardiovascular fanction because of their elongated shape, their wide variation in size and length, and because they had to adapt to extremely different habitats and gravitational influences. To keep the normal cardiovascular control the snakes developed anatomical and functional adaptations and interesting structural peculiarities are found in their autonomic, KKS, RAS and endothelin systems. Our laboratory has characterized some biochemical, pharmacological and physiological properties of these systems in South American snakes. This review compares the components and function of these systems in snakes and other vertebrates, and focuses on differences found in snakes, related with receptor or ligand structure and/or function in autonomic system, RAS and KKS, absence of components in KKS and the intriguing identity between a venom and a plasma component in the endothelin system. (c) 2006 Elsevier Inc. All rights reserved.
CitationComparative Biochemistry and Physiology A-molecular & Integrative Physiology. New York: Elsevier B.V., v. 147, n. 3, p. 766-778, 2007.
KeywordsAutonomic nervous system
- EPM - Outras produções 
Showing items related by title, author, creator and subject.
H-infinity state feedback switched control for discrete time-varying polytopic systems Deaecto, Grace S. [UNIFESP]; Geromel, Jose C. (Taylor & Francis Ltd, 2013-04-01)This article treats, in a new framework, a classical design problem, namely H state feedback switched control for discrete time-varying polytopic systems. the main goal is to jointly design a set of state feedback gains ...
The variability of baroreflex sensitivity in juvenile, spontaneously hypertensive rats Valenti, V. E. [UNIFESP]; Abreu, L. C. de; Colombari, E.; Sato, Monica Akemi [UNIFESP]; Ferreira, C. [UNIFESP] (Clinics Cardive Publ Pty Ltd, 2011-01-01)In this study the baroreflex sensitivity of conscious, juvenile, spontaneously hypertensive rats (SHRs) was compared. The study population consisted of 19 eight-week-old male SHRs. The baroreflex sensitivity was quantified ...
Adult spontaneously hypertensive rats from the same laboratory present different baroreflex gain Valenti, Vitor Engrácia [UNIFESP]; Moura Filho, Oseas Florencio de [UNIFESP]; Abreu, Luiz Carlos de [UNIFESP]; Ferreira, Celso [UNIFESP] (Drunpp-sarajevo, 2011-01-01)Background: A subset of normotensive Sprague-Dawley rats show lower baroreflex sensitivity; however, no previous study investigated whether there are differences in baroreflex sensitivity within this subset. Thus, we ...