Candidemia due to Candida tropicalis: clinical, epidemiologic, and microbiologic characteristics of 188 episodes occurring in tertiary care hospitals

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2007-05-01
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Nucci, Marcio
Colombo, Arnaldo L.
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Candida tropicalis is the 2nd most frequent agent of candidemia in Brazil (20-24%). We attempted to characterize the epidemiology, microbiology, and outcome of candidemia due to C. tropicalis by comparing patients with candidemia due to C. tropicalis with those with candidemia due to Candida albicans. Among the 924 episodes of candidemia, 188 (20%) were caused by c. Tropicalis. These cases were compared with 384 candidemias due to C. albicans. C. tropicalis was the 2nd most frequent species in adults (21.6%) and elderly patients patients, diabetes was the 2nd most frequent underlying disease. the only difference between C. tropicalis and C. albicans candidemia was a higher proportion of neuropenic patients in C. Tropicalis candidemia. C. tropicalis is a leading cause of candidemia in Brazil, and its epidemiology is similar to that of C. albicans. (c) 2007 Elsevier Inc. All rights reserved.
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Diagnostic Microbiology and Infectious Disease. New York: Elsevier B.V., v. 58, n. 1, p. 77-82, 2007.