Long-term evaluation of lipid profile and oral glucose tolerance test in Norplant (R) users

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Araujo, F. F.
Lima, G. R. de
Guazzelli, CAF
Barbieri, M.
Vigorito, N. M.
Lindsey, P. C.
Baracat, E. C.
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Purpose: This Study reports the results of the lipid profile and oral glucose tolerance test (OGTT) in 46 normal patients tested before and after 5 years of Norplant use.Results: After 5 years, there was a Substantial decrease of 28.9% in high-density lipoprotein cholesterol levels and a similar but less pronounced fall of 7.1% in the total cholesterol levels. the Castelli 1 index did not vary, and the triglycerides and low-density lipoprotein cholesterol levels remained normal and unchanged throughout the study period. All the mean values of OGTT were significantly lower after 5 years, except for the 90-min glycemia.Conclusion: These findings indicate that long-term Norplant use does not increase cardiovascular risks. (c) 2006 Elsevier Inc. All rights reserved.
Contraception. New York: Elsevier B.V., v. 73, n. 4, p. 361-363, 2006.