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dc.contributor.authorPeron, APDON
dc.contributor.authorSaraiva, R. M.
dc.contributor.authorAntonio, E. L.
dc.contributor.authorAndriolo, A.
dc.contributor.authorTucci, PJF
dc.date.accessioned2016-01-24T12:38:12Z
dc.date.available2016-01-24T12:38:12Z
dc.date.issued2005-12-01
dc.identifierhttp://dx.doi.org/10.1016/j.nutres.2005.10.003
dc.identifier.citationNutrition Research. Oxford: Pergamon-Elsevier B.V., v. 25, n. 12, p. 1075-1084, 2005.
dc.identifier.issn0271-5317
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/28583
dc.description.abstractPapillary muscle mechanics were studied in 4 groups of rats: control (C) noninfarcted (n = 9), C infarcted (n = 9), food-restricted (FR) noninfarcted (n = 8) and FR infarcted (n = 9). Food-restricted animals were fed with 50% of chow consumed by the C rats. Myocardial infarction (MI) was promoted 6 weeks after food restriction, and myocardial contraction and relaxation were studied 3 weeks thereafter. Interestingly, MI size was larger (P <.04) in C (50% +/- 8%) than in FR (40% +/- 10%) rats. Maximal developed tension, rate of tension rise and decay, resting tension, and time to 50% relaxation studied at calcium concentrations of 0.5, 1.0, 1.5, 2.0, and 2.5 mmol/L were essentially similar in the 4 groups. Infarcted and noninfarcted FR rats presented longer time to peak tension. These unprecedented data indicated that food restriction (1) seems to engender myocardial protection against ischemia/reperfusion injury and (2) does not affect myocardial mechanical function at the end of the healing period of MI. (c) 2005 Elsevier Inc. All rights reserved.en
dc.format.extent1075-1084
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofNutrition Research
dc.rightsAcesso restrito
dc.subjectfood restrictionen
dc.subjectmyocardial infarctionen
dc.subjectraten
dc.subjectsystolic functionen
dc.subjectdiastolic functionen
dc.subjectpapillary muscleen
dc.titleFood restriction does not impair myocardial mechanics during the healing period of myocardial infarction in the raten
dc.typeArtigo
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniversidade Federal de São Paulo, Dept Physiol, BR-04022000 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Med, BR-04022000 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Physiol, BR-04022000 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Med, BR-04022000 São Paulo, Brazil
dc.identifier.doi10.1016/j.nutres.2005.10.003
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000234281200005


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