Corneal endothelial deposits associated with rifabutin use
Coutinho, A. B.
Pereira, P. R.
Burnier, M. N.
Is part ofJournal of Ocular Pharmacology and Therapeutics
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Purpose: the aim of this study was to report on the possible development of corneal endothelial deposits resulting from the use of rifabutin.Methods: Case series consisting of 3 patients treated with rifabutin were retrospectively studied. Two of the patients were infected with human immunodeficiency virus. A corneal and external disease specialist performed a complete ophthalmologic exam and obtained medical histories of the patients.Results: All cases developed corneal endothelial deposits after previous use of rifabutin. the deposits were bilateral, yellow-white colored, stellate, and mainly peripheral.Conclusions: in these 3 cases, the unique positive ocular finding was corneal endothelial deposits, which may be related to the use of rifabutin.
CitationJournal of Ocular Pharmacology and Therapeutics. New Rochelle: Mary Ann Liebert Inc, v. 21, n. 2, p. 166-169, 2005.
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