The use of neoadjuvant chemotherapy to achieve complete surgical resection in recurring supratentorial anaplastic ependymoma

Abstract

Introduction: Ependymoma is a central nervous system neoplasm that is often managed with surgery and radiotherapy. the benefits of chemotherapy in treating this tumor remain poorly defined. Case report: the use of a platinum-based chemotherapy as a neoadjuvant treatment to permit complete surgical resection of a supratentorial anaplastic ependymoma recurring for the third time is described. Discussion: This paper also discusses the possible use of chemotherapy as a strategy that may allow tumor shrinkage and ease tumor resection in giant recurring ependymomas.