Evaluation of lipid profile in adolescents during long-term use of combined oral hormonal contraceptives

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Guazzelli, CAF
Lindsey, P. C.
Araujo, F. F. de
Barbieri, M.
Petta, C. A.
Aldrighi, J. M.
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The study evaluated the effects of the long-term use of a combined oral hormonal contraceptive containing 30 mug ethinyl estradiol and 75 mug gestodene in adolescents. Thirty-three volunteers, aged from 14 to 19 years, who used the oral contraceptive for three consecutive years, were studied. Evaluation of total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides was made before use and after 1, 2 and 3 years. During the 3-year study period, total cholesterol, HDL-C, LDL-C and triglyceride levels were significantly higher than previous measurements, but average values did not exceed the normal range.Compared to the first year, the second- and third-year cholesterol, HDL-C, LDL-C and triglyceride levels were not significantly different. (C) 2005 Elsevier Inc. All rights reserved.
Contraception. New York: Elsevier B.V., v. 71, n. 2, p. 118-121, 2005.