Genetic control of natural resistance of mouse macrophages to Coxiella burnetii infection in vitro: Macrophages from restrictive strains control parasitophorous vacuole maturation

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dc.contributor.author Zamboni, Dario Simões [UNIFESP]
dc.date.accessioned 2016-01-24T12:37:04Z
dc.date.available 2016-01-24T12:37:04Z
dc.date.issued 2004-04-01
dc.identifier http://dx.doi.org/10.1128/IAI.72.4.2395-2399.2004
dc.identifier.citation Infection and Immunity. Washington: Amer Soc Microbiology, v. 72, n. 4, p. 2395-2399, 2004.
dc.identifier.issn 0019-9567
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/27685
dc.description.abstract Macrophages from A/J and BALB/c mice were more susceptible to Coxiella burnetti phase II infection than were those from C57BL/6, C57BL/10, B10.A, C3H/HePas, and Swiss mice. Resistant macrophages effectively controlled the development of large replication vacuoles (LRVs), which accounted for the restriction of bacterial multiplication within the cultures. However, compared to fibroblasts, all macrophages controlled bacterial multiplication within LRVs. en
dc.format.extent 2395-2399
dc.language.iso eng
dc.publisher Amer Soc Microbiology
dc.relation.ispartof Infection and Immunity
dc.rights Acesso aberto
dc.title Genetic control of natural resistance of mouse macrophages to Coxiella burnetii infection in vitro: Macrophages from restrictive strains control parasitophorous vacuole maturation en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation UNIFESP, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifesp UNIFESP, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, Brazil
dc.identifier.file WOS000220481600065.pdf
dc.identifier.doi 10.1128/IAI.72.4.2395-2399.2004
dc.description.source Web of Science
dc.identifier.wos WOS:000220481600065



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