Providencia alcalifaciens strains translocate from the gastrointestinal tract and are resistant to lytic activity of serum complement

Date
2003-08-01Author
Vieira, ABR
Koh, IHJ
Guth, BEC
Type
ArtigoISSN
0022-2615Is part of
Journal of Medical MicrobiologyDOI
10.1099/jmm.0.04993-0Metadata
Show full item recordAbstract
The ability of Providencia alcalifaciens strains, isolated from patients with diarrhoeal disease, to translocate from the gastrointestinal tract and their resistance to serum complement lytic activity were investigated and compared with previously characterized differential invasive capabilities in HeLa cells. Translocation ability to several extraintestinal sites and resistance to lysis by human serum complement were observed in both highly invasive and non-invasive strains. These characteristics have not been previously described in P. alcalifaciens and their potential role in causing disseminated infections should therefore be considered.
Citation
Journal of Medical Microbiology. Reading: Soc General Microbiology, v. 52, n. 8, p. 633-636, 2003.Collections
- EPM - Artigos [17701]