Endocarditis due to glycopeptide-intermediate Staphylococcus aureus: case report and strain characterization

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2003-02-01
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We report a case of infective endocarditis due to vancomycin-intermediate Staphylococcus aureus (VISA) that did not respond to high doses of vancomycin. Initial vancomycin MIC of the last isolate recovered from blood was 8 1 mug/mL, but could be induced up to 32 mug/mL by consecutive growing with vancomycin. Clinical response was only accomplished when linezolid was included in therapy. (C) 2003 Elsevier Science Inc. All rights reserved.
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Diagnostic Microbiology and Infectious Disease. New York: Elsevier B.V., v. 45, n. 2, p. 149-152, 2003.
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