Prediction of pathological stage in prostate cancer through the percentage of involved fragments upon biopsy

Prediction of pathological stage in prostate cancer through the percentage of involved fragments upon biopsy

Author Dall'Oglio, Marcos Francisco Autor UNIFESP Google Scholar
Crippa, Alexandre Autor UNIFESP Google Scholar
Oliveira, Luis C. Autor UNIFESP Google Scholar
Neves Neto, Joao Ferreira Autor UNIFESP Google Scholar
Leite, Kátia Ramos Moreira Autor UNIFESP Google Scholar
Srougi, Miguel Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract INTRODUCTION: The need for defining the extension of disease in patients undergoing radical prostatectomy due to prostate adenocarcinoma is a relevant factor cure in such individuals. In order to identify a new independent preoperative factor for predicting the extension of prostate cancer, we assessed the role of the percentage of positive fragments upon biopsy. MATERIALS AND METHODS: A retrospective study compared the percentage of positive fragments on biopsy with the extension of disease as defined by the pathological examination of the surgical specimen from 898 patients undergoing radical prostatectomy due to clinically localized prostate cancer. RESULTS: On the univariate analysis, the percentage of positive fragments on biopsy showed a statistical significance for predicting confined disease (p < 0.001), which was found in 66.7% of the cases under study. Additionally, we observed that the total number of removed fragments exerts no influence on the extension of the disease (p = 0.567). CONCLUSION: the percentage of positive fragments is an independent factor for predicting the pathological stage of prostate adenocarcinoma, and the number of removed fragments is not related to the extension of the disease.
Keywords prostatic neoplasms
biopsy
needle
neoplasm staging
Language English
Date 2005-10-01
Published in International braz j urol. Sociedade Brasileira de Urologia, v. 31, n. 5, p. 445-451, 2005.
ISSN 1677-5538 (Sherpa/Romeo)
Publisher Sociedade Brasileira de Urologia
Extent 445-451
Origin http://dx.doi.org/10.1590/S1677-55382005000500005
Access rights Open access Open Access
Type Article
SciELO ID S1677-55382005000500005 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/2699

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