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dc.contributor.authorKonno, K.
dc.contributor.authorPalma, M. S.
dc.contributor.authorHitara, I. Y.
dc.contributor.authorJuliano, M. A.
dc.contributor.authorJuliano, L.
dc.contributor.authorYasuhara, T.
dc.identifier.citationToxicon. Oxford: Pergamon-Elsevier B.V., v. 40, n. 3, p. 309-312, 2002.
dc.description.abstractBradykinins were identified in three solitary wasp venoms. Purification and characterization of the venom extract of the scoliid wasp Megacampsomeris prismatica led to the identification of bradykinin and threonine(6)-bradykinin as the major peptide components. the survey of a number of extracts from solitary wasp venom by MALDI-TOF MS revealed that the venoms of two other scoliid wasps, Campsomeriella annulata annulata and Carinoscolia melanosoma fascinata, also contained Thr(6)-BK as one of the major components. Thus, this study showed the presence of bradykinins in some of the solitary wasp venoms. Moreover, it indicated that these peptides play a major role in their paralyzing action for prey capture because these bradykinins have been shown to block the synaptic transmission of the nicotinic acetylcholine receptor in the insect central nervous system. (C) 2001 Elsevier B.V. All rights reserved.en
dc.publisherElsevier B.V.
dc.rightsAcesso restrito
dc.subjectsolitary waspen
dc.subjectMALDI-TOF MSen
dc.titleIdentification of bradykinins in solitary wasp venomsen
dc.contributor.institutionSão Paulo State Univ
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionTokyo Univ Agr
dc.description.affiliationSão Paulo State Univ, Ctr Study Social Instects, Dept Biol, Inst Biosci Rio Claro, BR-13506900 Rio Claro, SP, Brazil
dc.description.affiliationFAPESP, CEPID, Ctr Appl Toxicol, BR-05468901 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Paulista Med Sch, Dept Biophys, BR-04044020 São Paulo, Brazil
dc.description.affiliationTokyo Univ Agr, Jr Coll Agr, Dept Nutr, Setagaya Ku, Tokyo 1568502, Japan
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Paulista Med Sch, Dept Biophys, BR-04044020 São Paulo, Brazil
dc.description.sourceWeb of Science

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