Comparison between human and armadillo Paracoccidioides brasiliensis isolates by random amplified polymorphic DNA analysis

Date
1998-01-01Author
Sano, A.
Tanaka, R.
Yokoyama, K.
Franco, M.
Bagagli, E.
Montenegro, M. R.
Mikami, Y.
Miyaji, M.
Nishimura, K.
Type
ArtigoISSN
0301-486XIs part of
MycopathologiaDOI
10.1023/A:1006949113529Metadata
Show full item recordAbstract
Sixty-three Paracoccidioides brasiliensis isolates obtained from three nine-banded armadillos (Dasypus novem-cinctus), one Amazonian armadillo's and 19 clinical isolates were compared by random amplified polymorphic DNA analysis with the primer OPG-19. the isolates were divided into three major clusters, I, II and III. Coincidences between human and armadillo isolates were observed in clusters I and II. Cluster III consisted only of armadillos' isolates. the results suggested that (I) humans may acquire P. brasiliensis infection by contact with armadillo's environment, (II) there may be P. brasiliensis genotypes peculiar to the animal, and (III) individual armadillos may be infected with P brasiliensis cells with different genotypes.
Citation
Mycopathologia. Dordrecht: Kluwer Academic Publ, v. 143, n. 3, p. 165-169, 1998.Keywords
armadilloParacoccidioides brasiliensis
PCR
RAPD
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