COMPARISON BETWEEN CLEARANCE RATES of PLASMA KALLIKREIN and of PLASMA KALLIKREIN-ALPHA-MACROGLOBULIN COMPLEXES BY the LIVER
Borges, D. R.
Is part ofInternational Journal of Biochemistry
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1. Alpha-Macroglobulins (alphaMs) were isolated from the serum of injured rats through a two-stage method: gel filtration and ultracentrifugation.2. the clearance rates of rat plasma kallikrein (RPK) and alphaMs-RPK complexes were compared in an isolated rat liver perfusion system: the alphaMs-RPK complexes are cleared at a much slower rate (half-life ranging from 24 to > 120 min) than does RPK itself (half-life ranging from 13 to 18 min).
CitationInternational Journal of Biochemistry. Oxford: Pergamon-Elsevier B.V., v. 25, n. 7, p. 1047-1051, 1993.
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