MODELING the INTERACTION BETWEEN AIDS and TUBERCULOSIS

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Data
1993-05-01
Autores
Massad, E.
Burattini, Marcelo Nascimento [UNIFESP]
Coutinho, FAB
Yang, H. M.
Raimundo, S. M.
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A deterministic model is proposed for the study of the dynamics of acquired immunodeficiency syndrome (AIDS) and tuberculosis (TB) co-infection. the model is comprised by a set of sixteen ordinary differential equations representing different states of both diseases, and it is intended to provide a theoretical framework for the study of the interaction between both infections. Numerical simulations of the model resulted in three striking outcomes: first, the pathogenicity of Human Immunodeficiency Virus (HIV) is enhanced by the presence of TB, and vice-versa; second, the prevalence of AIDS is higher in the presence of TB; and third, relative risk analysis demonstrated a much stronger influence of AIDS on TB than the other way around.
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Mathematical and Computer Modelling. Oxford: Pergamon-Elsevier B.V., v. 17, n. 9, p. 7-21, 1993.
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