Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans
Frochtengarten, Mario Luiz [UNIFESP]
Is part ofPhytotherapy Research
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Passiflora species are used in folk medicine as hypnotic and sedative treatments. in this study the hypnotic-sedative effects and toxicity of Passiflora edulis were assessed in rats and mice and in healthy volunteers. It was verified that some samples of Passiflora edulis had a nonspecific central nervous system depressant effect. Furthermore, hepatobiliary and pancreatic toxicity to animals and humans were detected.
CitationPhytotherapy Research. W Sussex: John Wiley & Sons Ltd, v. 5, n. 6, p. 262-266, 1991.
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