Aspectos genéticos do transtorno obsessivo-compulsivo
Gonzalez, Christina H [UNIFESP]
Is part ofRevista Brasileira de Psiquiatria
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Since the first descriptions of obsessive-compulsive disorder (OCD), genetic factors have been implicated in the etiology of the illness. Twin studies show a high concordance rate for monozygotic twins. Family studies found a higher risk for OCD among relatives of OCD patients. Segregation analysis studies suggest the possible role of a major effect gene in the etiology of OCD. Association studies using molecular techniques have been conducted to try to find a specific gene or polymorphism involved in OCD. This review outlines the evidence gathered to date, including the recent findings in the molecular genetics analysis.
CitationRevista Brasileira de Psiquiatria. Associação Brasileira de Psiquiatria - ABP, v. 23, p. 38-41, 2001.
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