Cluster of Candida parapsilosis primary bloodstream infection in a neonatal intensive care unit
Pessoa-Silva, Carmem Lucia [UNIFESP]
Santos, Rosana M. R. Dos
Colombo, Arnaldo Lopes [UNIFESP]
Is part ofBrazilian Journal of Infectious Diseases
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Candida parapsilosis is an increasingly important bloodstream pathogen in neonatal intensive care units (NICU). We investigated a cluster of bloodstream infections in a NICU to determine whether nosocomial transmission occurred. During a 3-day period, 3 premature infants hospitalized in the same unit presented with sepsis caused by C. parapsilosis. Electrophoretic karyotype of the organisms was performed by using pulsed field gel electrophoresis in a countour-clamped homogeneous electric field system. The isolate from 1 newborn could not be typed, and the isolates from the remaining 2 infants had identical patterns. All 3 cases are described. We conclude that nosocomial transmission of C. parapsilosis occurred and that neonates under intensive care may represent a risk group for this pathogen.
CitationBrazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 5, n. 1, p. 32-36, 2001.
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