Browsing Em verificação - Geral by Title
Now showing items 1-20 of 7517
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1,4-Diamino-2-butanone, a putrescine analogue, promotes redox imbalance in Trypanosoma cruzi and mammalian cells
(Elsevier B.V., 2012-12-15)The putrescine analogue 1,4-diamino-2-butanone (DAB) is highly toxic to various microorganisms, including Trypanosoma cruzi. Similar to other a-aminocarbonyl metabolites. DAB exhibits pro-oxidant properties. DAB undergoes ...
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1-[(Z)-1-Bromo-2-(butyldichloro-lambda(4)tellanyl)ethenyl]cyclohex-1-ene
(Wiley-Blackwell, 2011-07-01)The Te-IV atom in the title compound, [Te(C4H9)(C8H10Br)Cl-2] or C12H19BrCl2Te, is in a distorted psi-trigonal-bipyramidal geometry, with the lone pair of electrons projected to occupy a position in the equatorial plane, ...
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1.70 angstrom X-ray structure of human apo kallikrein 1: Structural changes upon peptide inhibitor/substrate binding
(Wiley-Blackwell, 2005-03-01)Human kallikreins are serine proteases that comprise a recently identified large and closely related 15-member family. the kallikreins include both regulatory- and degradative-type proteases, impacting a variety of ...
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A 12-wk follow-up study to evaluate the effects of mixing insulin lispro and insulin glargine in young individuals with type 1 diabetes
(Wiley-Blackwell, 2012-11-01)Objective: This study was performed to compare in real-life conditions the serum profile of insulin lispro (IL) after a subcutaneous (SC) injection, separate and mixed with insulin glargine (IG), using a sensitive ...
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17-hydroxylase/C17,20-lyase (CYP17) is not the enzyme responsible for side-chain cleavage of cortisol and its metabolites
(Elsevier B.V., 2008-07-01)The question addressed in this study was the nature of the enzyme required to remove the side-chain of 17-hydroxycorticosteroids, leading in the case of cortisol to the excretion of 11 beta-hydroxyandrosterone, 11-oxo-androsterone ...
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17p duplicated Charcot-Marie-Tooth 1A - Characteristics of a new population
(Dr Dietrich Steinkopff Verlag, 2005-08-01)The most frequent type of Charcot-Marie-Tooth (CMT) neuropathy is that associated with the 17p11.2-p12 chromosome duplication, whose characteristics have been well described in European and North American populations. in ...
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An 18-Week, Prospective, Randomized, Double-Blind, Multicenter Study of Amlodipine/Ramipril Combination Versus Amlodipine Monotherapy in the Treatment of Hypertension: the Assessment of Combination Therapy of Amlodipine/Ramipril (ATAR) Study
(Elsevier B.V., 2008-09-01)Background: A combination of antihypertensive agents of different drug classes in a fixed-dose combination (FDC) may offer advantages in terms of efficacy, tolerability, and treatment compliance. Combination of a calcium ...
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2 RECEPTOR SUBTYPES ARE INVOLVED in the CONTRACTILE COMPONENT of the GUINEA-PIG ILEUM RESPONSES TO ENDOTHELINS
(Lippincott-raven Publ, 1993-01-01)Endothelin-I (ET-1) and endothelin-3 (ET-3) induced a biphasic response (relaxation and contraction) in the guinea pig ileum. Short-term activation of protein kinase C (PKC) with phorbol 12,13-dibutyrate (PDBu) inhibited ...
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2-chlorovinyl tellurium dihalides, (p-tol)Te[C(H)=C(Cl)Ph]X2 for X = Cl, Br and I: variable coordination environments, supramolecular structures and docking studies in cathepsin B
(Sociedade Brasileira de Química, 2010-01-01)Crystallography shows that the Te atom in each of (p-tol)Te[C(H)=C(Cl)Ph]X2, for X = Cl (1), Br (2) and I (3), is within a distorted Ψ-pentagonal bipyramidal geometry. An E configuration for the vinyl group in (1) precludes ...
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2. Monitorização dos parâmetros hematimétricos
(Sociedade Brasileira de Nefrologia, 2014-03-01) -
25-Hydroxyvitamin D level does not reflect intestinal calcium absorption: an assay using strontium as a surrogate marker
(Springer, 2015-05-01)There is conflicting evidence as to the optimal serum 25-hydroxyvitamin D [25(OH)D] concentration for intestinal calcium absorption (Abs-Ca). Our purpose was to assess the relationship between vitamin D status and Abs-Ca ...
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THE 35/50 KDA SURFACE-ANTIGEN of TRYPANOSOMA-CRUZI METACYCLIC TRYPOMASTIGOTES, AN ADHESION MOLECULE INVOLVED in HOST-CELL INVASION
(Blackwell Science Ltd, 1993-02-01)We have previously shown that monoclonal antibodies directed to the 90 kDa glycoprotein and the 35150 kDa glycoconjugate, present on the surface of Trypansoma cruzi metacyclic trypomastigotes, inhibited host cell invasion. ...
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A 36-residue peptide contains all of the information required for 7B2-mediated activation of prohormone convertase 2
(Amer Soc Biochemistry Molecular Biology Inc, 1999-07-23)The prohormone convertases (PCs) are serine proteinases responsible for the processing of secretory protein precursors. PC2 is the only member of this family whose activation requires intracellular interaction with a helper ...
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3q27 Aberrations in a Childhood Ovary Teratoma With Associated Malignant Germ Cell Component
(Wiley-Blackwell, 2009-03-01)Cytogenetic Studies of childhood ovary tumors have been poorly described. in the present article, the cytogenetic findings of an ovarian teratoma with malignant germ cell (yolk-sac) component occurring in an 8-year-old ...
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3º Consenso Brasileiro para pesquisa de autoanticorpos em células HEp-2 (FAN): recomendações para padronização do ensaio de pesquisa de autoanticorpos em células HEp-2, controle de qualidade e associações clínicas
(Sociedade Brasileira de Reumatologia, 2009-04-01)OBJECTIVE: The Third Brazilian Consensus for autoantibodies Screening in HEp-2 cells had as purpose the evaluation of difficulties in the accomplishment of the 2nd Consensus recommendations that took place in the year of ...
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5' hypersensitive site-2 and fetal hemoglobin in Brazilians
(Marcel Dekker Inc, 1996-01-01) -
5,10-methylenetetrahydrofolate reductase polymorphisms and acute lymphoblastic leukemia risk: A meta-analysis
(Amer Assoc Cancer Research, 2006-10-01)There is evidence supporting a role for 5-10 methylenetetra-hydrofolate reductase (MTHFR) gene variants in acute lymphoblastic leukemia (ALL). To provide a more robust estimate of the effect of MTHFR polymorphisms on the ...
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5-(4-Fluorophenyl)-2,2,6-trimethyl-4H-1,3-dioxin-4-one
(Wiley-Blackwell, 2009-07-01)The 1,3-dioxine ring in the title compound, C(13)H(13)FO(3), is in a half-boat conformation with the methyl-bonded C atom 0.612 (2) angstrom out of the plane defined by the remaining five atoms.
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The 5th International Conference on Magnetic Refrigeration, THERMAG V, in Grenoble
(Elsevier B.V., 2013-08-01) -
The A(1) receptor agonist R-Pia reduces the imbalance between cerebral glucose metabolism and blood flow during status epilepticus: Could this mechanism be involved with neuroprotection?
(Elsevier B.V., 2011-01-01)It is well known that the uncoupling between local cerebral glucose utilization (LCGU) and local cerebral blood flow (LCBF), i.e. decrease in LCBF rates with high LCGU, is frequently associated with seizure-induced neuronal ...
