Now showing items 1-20 of 23969

    • Outcomes of 847 childhood-onset systemic lupus erythematosus patients in three age groups 

      Lopes, S. R. M.; Gormezano, N. W. S.; Gomes, R. C.; Aikawa, N. E.; Pereira, R. M. R.; Terreri, M. T. [UNIFESP]; Magalhaes, C. S.; Ferreira, J. C.; Okuda, E. M.; Sakamoto, A. P. [UNIFESP]; Sallum, A. M. E.; Appenzeller, S.; Ferriani, V. P. L.; Barbosa, C. M.; Lotufo, S.; Jesus, A. A.; Andrade, L. E. C. [UNIFESP]; Campos, L. M. A.; Bonfa, E.; Silva, C. A. (Sage Publications Ltd, 2017)
      Objective The objective of this study was to assess outcomes of childhood systemic lupus erythematosus (cSLE) in three different age groups evaluated at last visit: group A early-onset disease (<6 years), group B school ...

    • Short Form Health Survey (sf-36) differs between genotypic groups of patients with suspected hereditary hemochromatosis 

      Fernanda, Paula; Cancado, Rodolfo; Naoum, Flavio; Dinardo, Carla; Fonseca, Guilherme; Gualandro, Sandra; Krieger, Jose; Pereira, Alexandre; Brissot, Pierre; Santos, Paulo [UNIFESP] (Wiley, 2017)
    • Chronic lymphocytic leukemia in Brazil: A retrospective analysis of 1903 cases 

      Goncalves, Matheus Vescovi [UNIFESP]; Rodrigues, Celso Arrais [UNIFESP]; Heidemarie Lorand Metze, Irene Gyongyver; Lacerda, Marcelo Pitombeira [UNIFESP]; Lopes Ferrari Chauffaille, Maria de Lourdes [UNIFESP]; Azevedo, Alita; Machado, Cintia; Chiattone, Carlos Sergio; Fortier, Sergio; Perobelli, Leila; Valerio Ikoma, Maura Rosane; Clementino, Nelma; Hamerschlak, Nelson; Sthel, Vivia Machado; Mendes Ommati, Larissa Veloso; Cordeiro de Farias, Danielle Leao; Duarte, Fernando Barroso; Buccheri, Valeria; de Azambuja, Ana Paula; de Almeida, Denise Ramos; Piratininga Figueiredo, Vera Lucia; Yamamoto, Mihoko [UNIFESP] (Wiley, 2017)
    • Aerobic exercise reduces hippocampal ERK and p38 activation and improves memory of middle-aged rats 

      Cardoso, Fabrizio dos Santos; Franca, Erivelton Fernandes; Serra, Fernando Tadeu; Victorino, Angelica Begatti [UNIFESP]; de Almeida, Alexandre Aparecido [UNIFESP]; Fernandes, Jansen [UNIFESP]; Cabral, Francisco Romero; Venancio, Daniel Paulino; Arida, Ricardo Mario [UNIFESP]; da Silva, Sergio Gomes (Wiley, 2017)
      Aging is often accompanied by cognitive decline, memory impairment, and an increased susceptibility to neurodegenerative disorders. Although the physiological processes of aging are not fully understood, these age-related ...

    • Inflammasome gene profile is modulated in septic patients, with a greater magnitude in non-survivors 

      Esquerdo, K. F. [UNIFESP]; Sharma, N. K. [UNIFESP]; Brunialti, M. K. C. [UNIFESP]; Baggio-Zappia, G. L. [UNIFESP]; Assuncao, M.; Azevedo, L. C. P.; Bafi, A. T. [UNIFESP]; Salomao, R. [UNIFESP] (Wiley, 2017)
      Inflammasome signalling induces the processing and secretion of interleukin (IL)-1 and IL-18 which, coupled with pyroptosis, activate further the inflammatory response. In the present study we evaluated the expression of ...

    • Organizational Issues, Structure, and Processes of Care in 257 ICUs in Latin America: A Study From the Latin America Intensive Care Network 

      Estenssoro, Elisa; Alegria, Leyla; Murias, Gaston; Friedman, Gilberto; Castro, Ricardo; Vaeza, Nicolas Nin; Loudet, Cecilia; Bruhn, Alejandro; Jibaja, Manuel; Ospina-Tascon, Gustavo; Rios, Fernando; Machado, Flavia R. [UNIFESP]; Cavalcanti, Alexandre Biasi; Dubin, Arnaldo; Hurtado, F. Javier; Briva, Arturo; Romero, Carlos; Bugedo, Guillermo; Bakker, Jan; Cecconi, Maurizio; Azevedo, Luciano [UNIFESP]; Hernandez, Glenn (Lippincott Williams & Wilkins, 2017)
      Objective: Latin America bears an important burden of critical care disease, yet the information about it is scarce. Our objective was to describe structure, organization, processes of care, and research activities in ...

    • Production of primordial gravitational waves in a simple class of running vacuum cosmologies 

      Tamayo, D. A.; Lima, J. A. S.; Bessada, D. F. A. [UNIFESP] (World Scientific Publ Co Pte Ltd, 2017)
      The problem of cosmological production of gravitational waves (GWs) is discussed in the framework of an expanding, spatially homogeneous and isotropic FRW type universe with time-evolving vacuum energy density. The GW ...

    • Physiological Requirements to Perform the Glittre Activities of Daily Living Test by Subjects With Mild-to-Severe COPD 

      Souza, Gerson F. [UNIFESP]; Moreira, Graciane L. [UNIFESP]; Tufanin, Andrea [UNIFESP]; Gazzotti, Mariana R. [UNIFESP]; Castro, Antonio A. [UNIFESP]; Jardim, Jose R. [UNIFESP]; Nascimento, Oliver A. [UNIFESP] (Daedalus Enterprises Inc, 2017)
      BACKGROUND: The Glittre activities of daily living (ADL) test is supposed to evaluate the functional capacity of COPD patients. The physiological requirements of the test and the time taken to perform it by COPD patients ...

    • Frequent Tn2 Misannotation in the Genetic Background of rmtB 

      Martins, Willames M. B. S. [UNIFESP]; Gales, Ana C. [UNIFESP] (Amer Soc Microbiology, 2017)
    • The Influence of Income and Formal Education on Damage in Brazilian Patients With Systemic Lupus Erythematosus 

      de Andrade Teixeira, Roberto Cordeiro; Borba Neto, Eduardo Ferreira; Christopoulos, Georges Basile; Sato, Emilia Inoue [UNIFESP] (Lippincott Williams & Wilkins, 2017)
      Objective: The aim of this study was to evaluate the association of socioeconomic status and American College of Rheumatology/Systemic Lupus International Collaborating Clinics Damage Index (SDI) score in Brazilian patients ...

    • Sleep awareness and education among clinical practitioners 

      Kim, Lenise Jihe [UNIFESP]; Tufik, Sergio [UNIFESP]; Andersen, Monica Levy [UNIFESP] (Roy Coll Phys London Editorial Office, 2017)
    • Regional differences in the management and outcome of kidney transplantation in patients with human immunodeficiency virus infection: A 3-year retrospective cohort study 

      Cristelli, Marina P. [UNIFESP]; Cofan, Federico; Tedesco-Silva, Helio [UNIFESP]; Trullas, Joan Carles; Santos, Daniel Wagner C. L. [UNIFESP]; Manzardo, Christian; Aguero, Fernando; Moreno, Asuncion; Oppenheimer, Federico; Diekmann, Fritz; Medina-Pestana, Jose O. [UNIFESP]; Miro, Jose Maria (Wiley, 2017)
      Background: In the developed world, kidney transplantation (KT) in patients with human immunodeficiency virus (HIV) infection is well established. Developing countries concentrate 90% of the people living with HIV, but ...

    • Distress and psychosocial needs: Insights to address health inequities in Brazil 

      Bergerot, Cristiane Decat; Okuma, Getulio Yuzo [UNIFESP]; Marcusso Manhaes, Maria Fernanda [UNIFESP]; Ashing, Kimlin Tam (Wiley, 2017)
    • Preliminary data on perceived cognitive function in Brazilian breast cancer survivors 

      Bergerot, Cristiane Decat; Pedras, Renata Nunes [UNIFESP]; Bergerot, Paulo Gustavo; Elias, Simone [UNIFESP]; Lopes De Domenico, Edvane Birelo [UNIFESP] (Wiley, 2017)
    • Emotional and physical late effect of testicular cancer treatment: Implications for follow-up 

      Bergerot, Paulo Gustavo; Bergerot, Cristiane Decat; Marcusso Manhaes, Maria Fernanda [UNIFESP]; Pal, Sumanta K.; Philip, Errol J. (Wiley, 2017)
    • Factors associated with distress in patients with incurable cancer: addressing disparities at distinct healthcare system in Brazil 

      Bergerot, Cristiane Decat; Philip, Errol J.; Bergerot, Paulo Gustavo; Pedras, Renata Nunes [UNIFESP]; Ashing, Kimlin Tam (Wiley, 2017)
    • Convergent Total Synthesis of (+/-)-Apomorphine via Benzyne Chemistry: Insights into the Mechanisms Involved in the Key Step 

      Muraca, Ana Carolina A. [UNIFESP]; Perecim, Givago P. [UNIFESP]; Rodrigues, Alessandro [UNIFESP]; Raminelli, Cristiano [UNIFESP] (Georg Thieme Verlag Kg, 2017)
      Convergent total synthesis of (+/-)-apomorphine hydrochloride was accomplished by an approach that employs in the key step a sequence of transformations involving a [4+2]-cycloaddition reaction followed by a hydrogen ...

    • Adipose Derived Cells and Tissues for Regenerative Medicine 

      Gimble, Jeffrey M.; Ray, Stephen P.; Zanata, Fabiana [UNIFESP]; Wu, Xiying; Wade, James; Khoobehi, Kamran; Ferreira, Lydia Masako [UNIFESP]; Bunnell, Bruce A. (Amer Chemical Soc, 2017)
      Adipose tissue is now recognized as a complex organ serving endocrine, immune, and metabolic functions. Adipose depots are composed of mature adipocytes as well as stromal vascular fraction (SVF) cells, a heterogeneous ...

    • Gene expression profile in heat-shocked Holstein and Nelore oocytes and cumulus cells 

      Ticianelli, J. S.; Emanuelli, I. P.; Satrapa, R. A.; Castilho, A. C. S.; Loureiro, B.; Sudano, M. J.; Fontes, P. K.; Pinto, R. F. P.; Razza, E. M.; Surjus, R. S.; Sartori, R.; Assumpcao, M. E. O. A.; Visintin, J. A.; Barros, C. M.; Paula-Lopes, F. F. [UNIFESP] (Csiro Publishing, 2017)
      The present study determined the transcriptome profile in Nelore and Holstein oocytes subjected to heat shock during IVM and the mRNA abundance of selected candidate genes in Nelore and Holstein heat-shocked oocytes and ...

    • Immune checkpoint inhibitors for advanced non-small cell lung cancer: emerging sequencing for new treatment targets 

      Aguiar, Pedro Nazareth; De Mello, Ramon Andrade; Noia Barreto, Carmelia Maria [UNIFESP]; Perry, Luke Alastair; Penny-Dimri, Jahan; Tadokoro, Hakaru [UNIFESP]; Lopes, Gilberto de Lima (Bmj Publishing Group, 2017)
      Lung cancer is the leading cause of cancer-related deaths in the world. Immune checkpoint inhibitors (ICI) stimulate cytotoxic lymphocyte activity against tumour cells. These agents are available for the treatment of ...