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Does Obstructive Sleep Apnea Impair the Cardiopulmonary Response to Exercise?
(Amer Acad Sleep Medicine, 2013-04-01)
Study Objectives: the aim of this study was to evaluate cardiopulmonary exercise performance in lean and obese patients with obstructive sleep apnea (OSA) compared with controls.Design: Case-control study.Setting: the study ...
Influence of genotype on dopamine transporter availability in human striatum and sleep architecture
(Elsevier B.V., 2010-09-30)
Genetic variants may modulate dopamine transporter (DAT) availability in the brain. A polymorphism within the intron 8 of the DAT1 gene was evaluated in 27 healthy men. No correlation between Int8 VNTR and either the ...
Addictive potential of modafinil and cross-sensitization with cocaine: a pre-clinical study
(Wiley-Blackwell, 2011-10-01)
Repeated or even a single exposure to drugs of abuse can lead to persistent locomotor sensitization, which is the result of an abundance of neuroplastic changes occurring within the circuitry involved in motivational ...
Blockage of dopaminergic D-2 receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation
(Elsevier B.V., 2008-04-09)
Dopamine (DA) has, as of late, become singled out from the profusion of other neurotransmitters as what could be called a key substance, in the regulation of the sleep-wake states. We have hypothesized that dopaminergic ...
Risk factors, biochemical markers, and genetic polymorphisms in early coronary artery disease
(Sociedade Brasileira de Cardiologia - SBC, 2003-04-01)
OBJECTIVE: To assess the risk factors, lipid and apolipoprotein profile, hemostasis variables, and polymorphisms of the apolipoprotein AI-CIII gene in early coronary artery disease (CAD). METHODS: Case-control study with ...
Influence of genetic ancestry on the risk of obstructive sleep apnoea syndrome
(European Respiratory Soc Journals Ltd, 2010-10-01)
The aim of the present study was to evaluate the influence of ethnicity on the risk of developing obstructive sleep apnoea syndrome (OSAS) using genomic analysis methods to estimate ancestry.DNA samples were obtained from ...
Physiological and electroencephalographic responses to acute exhaustive physical exercise in people with juvenile myoclonic epilepsy
(Elsevier B.V., 2011-12-01)
Although the available evidence suggests that exercise may positively affect epilepsy, whether this effect is applicable to different types of epilepsy has not been established. Physiological responses during rest, acute ...
Dietary Patterns, Metabolic Markers and Subjective Sleep Measures in Resident Physicians
(Informa Healthcare, 2013-01-01)
Shiftwork is common in medical training and is necessary for 24-h hospital coverage. Shiftwork poses difficulties not only because of the loss of actual sleep hours but also because it can affect other factors related to ...
Intrinsically Photosensitive Retinal Ganglion Cell Activity Is Associated with Decreased Sleep Quality in Patients with Glaucoma
(Elsevier B.V., 2015-06-01)
Purpose: To use the pupillary light reflex and polysomnography to evaluate the function of intrinsically photosensitive retinal ganglion cells (ipRGCs) and to correlate this function with structural damage in glaucoma.Design: ...
Sleep in Postmenopausal Women
(Sage Publications Inc, 2012-04-01)
The aim of this study was to identify factors that most influence the perception of sleep quality in postmenopausal women. We used the methodological strategy of the Collective Subject Discourse (CSD), which is based on a ...