Recent Submissions

  • Outcomes of 847 childhood-onset systemic lupus erythematosus patients in three age groups 

    Lopes, S. R. M.; Gormezano, N. W. S.; Gomes, R. C.; Aikawa, N. E.; Pereira, R. M. R.; Terreri, M. T. [UNIFESP]; Magalhaes, C. S.; Ferreira, J. C.; Okuda, E. M.; Sakamoto, A. P. [UNIFESP]; Sallum, A. M. E.; Appenzeller, S.; Ferriani, V. P. L.; Barbosa, C. M.; Lotufo, S.; Jesus, A. A.; Andrade, L. E. C. [UNIFESP]; Campos, L. M. A.; Bonfa, E.; Silva, C. A. (Sage Publications Ltd, 2017)
    Objective The objective of this study was to assess outcomes of childhood systemic lupus erythematosus (cSLE) in three different age groups evaluated at last visit: group A early-onset disease (<6 years), group B school ...

  • Aerobic exercise reduces hippocampal ERK and p38 activation and improves memory of middle-aged rats 

    Cardoso, Fabrizio dos Santos; Franca, Erivelton Fernandes; Serra, Fernando Tadeu; Victorino, Angelica Begatti [UNIFESP]; de Almeida, Alexandre Aparecido [UNIFESP]; Fernandes, Jansen [UNIFESP]; Cabral, Francisco Romero; Venancio, Daniel Paulino; Arida, Ricardo Mario [UNIFESP]; da Silva, Sergio Gomes (Wiley, 2017)
    Aging is often accompanied by cognitive decline, memory impairment, and an increased susceptibility to neurodegenerative disorders. Although the physiological processes of aging are not fully understood, these age-related ...

  • Inflammasome gene profile is modulated in septic patients, with a greater magnitude in non-survivors 

    Esquerdo, K. F. [UNIFESP]; Sharma, N. K. [UNIFESP]; Brunialti, M. K. C. [UNIFESP]; Baggio-Zappia, G. L. [UNIFESP]; Assuncao, M.; Azevedo, L. C. P.; Bafi, A. T. [UNIFESP]; Salomao, R. [UNIFESP] (Wiley, 2017)
    Inflammasome signalling induces the processing and secretion of interleukin (IL)-1 and IL-18 which, coupled with pyroptosis, activate further the inflammatory response. In the present study we evaluated the expression of ...

  • Production of primordial gravitational waves in a simple class of running vacuum cosmologies 

    Tamayo, D. A.; Lima, J. A. S.; Bessada, D. F. A. [UNIFESP] (World Scientific Publ Co Pte Ltd, 2017)
    The problem of cosmological production of gravitational waves (GWs) is discussed in the framework of an expanding, spatially homogeneous and isotropic FRW type universe with time-evolving vacuum energy density. The GW ...

  • Physiological Requirements to Perform the Glittre Activities of Daily Living Test by Subjects With Mild-to-Severe COPD 

    Souza, Gerson F. [UNIFESP]; Moreira, Graciane L. [UNIFESP]; Tufanin, Andrea [UNIFESP]; Gazzotti, Mariana R. [UNIFESP]; Castro, Antonio A. [UNIFESP]; Jardim, Jose R. [UNIFESP]; Nascimento, Oliver A. [UNIFESP] (Daedalus Enterprises Inc, 2017)
    BACKGROUND: The Glittre activities of daily living (ADL) test is supposed to evaluate the functional capacity of COPD patients. The physiological requirements of the test and the time taken to perform it by COPD patients ...

  • The Influence of Income and Formal Education on Damage in Brazilian Patients With Systemic Lupus Erythematosus 

    de Andrade Teixeira, Roberto Cordeiro; Borba Neto, Eduardo Ferreira; Christopoulos, Georges Basile; Sato, Emilia Inoue [UNIFESP] (Lippincott Williams & Wilkins, 2017)
    Objective: The aim of this study was to evaluate the association of socioeconomic status and American College of Rheumatology/Systemic Lupus International Collaborating Clinics Damage Index (SDI) score in Brazilian patients ...

  • A Novel Anti-Pollution Filter for Volatile Agents During Cardiopulmonary Bypass: Preliminary Tests 

    Nigro Neto, Caetano; Landoni, Giovanni; Tardelli, Maria Angela [UNIFESP] (W B Saunders Co-Elsevier Inc, 2017)
    Objective: Concerns regarding pollution of the operating room by volatile anesthetics and effects on atmospheric ozone depletion exist. Volatile agents commonly are used during cardiopulmonary bypass to provide anesthesia ...

  • Efficacy of 8-and 4-Session Mindfulness-Based Interventions in a Non-clinical Population: A Controlled Study 

    Demarzo, Marcelo [UNIFESP]; Montero-Marin, Jesus; Puebla-Guedea, Marta; Navarro-Gil, Mayte; Herrera-Mercadal, Paola; Moreno-Gonzalez, Sergio; Calvo-Carrion, Sandra; Bafaluy-Franch, Laura; Garcia-Campayo, Javier (Frontiers Media Sa, 2017)
    Background: Many attempts have been made to abbreviate mindfulness programmes in order to make them more accessible for general and clinical populations while maintaining their therapeutic components and efficacy. The aim ...

  • Gender Parity in Critical Care Medicine 

    Mehta, Sangeeta; Burns, Karen E. A.; Machado, Flavia R. [UNIFESP]; Fox-Robichaud, Alison E.; Cook, Deborah J.; Calfee, Carolyn S.; Ware, Lorraine B.; Burnham, Ellen L.; Kissoon, iranjan; Marshall, John C.; Mancebo, Jordi; Finfer, Simon; Hartog, Christiane; Reinhart, Konrad; Maitland, Kathryn; Stapleton, Renee D.; Kwizera, Arthur; Amin, Pravin; Abroug, Fekri; Smith, Orla; Laake, Jon H.; Shrestha, Gentle S.; Herridge, Margaret S. (Amer Thoracic Soc, 2017)
    Clinical practice guidelines are systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances. These documents inform and shape patient ...

  • Ga-68-DOTATATE PET/CT in recurrent medullary thyroid carcinoma: a lesion-by-lesion comparison with In-111-octreotide SPECT/CT and conventional imaging 

    Itaya Yamaga, Lilian Yuri; Cunha, Marcelo L.; Campos Neto, Guilherme C.; Garcia, Marcio R. T.; Yang, Ji H. [UNIFESP]; Camacho, Cleber P. [UNIFESP]; Wagner, Jairo; Funari, Marcelo B. G. (Springer, 2017)
    Purpose The aim of this study was to prospectively compare the detection rate of Ga-68-DOTATATE PET-CT with In-111-octreotide SPECT-CT and conventional imaging (CI) in medullary thyroid carcinoma (MTC) patients with increased ...

  • Delivering education to the poor: investigating the role of self-motivation in Brazil 

    Andrews, Christina W. [UNIFESP]; Rezende, Simone; Almeida, Wilson M. (Sage Publications Ltd, 2017)
    In this multiple-case study, which involved seven municipalities in Brazil, we argue that good education is a by-product from educators' commitment, which in turn is explained through self-determination theory. The research ...

  • The intensive care medicine research agenda on septic shock 

    Perner, Anders; Gordon, Anthony C.; Angus, Derek C.; Lamontagne, Francois; Machado, Flavia [UNIFESP]; Russell, James A.; Timsit, Jean-Francois; Marshall, John C.; Myburgh, John; Shankar-Hari, Manu; Singer, Mervyn (Springer, 2017)
    Septic shock remains a global health challenge with millions of cases every year, high rates of mortality and morbidity, impaired quality of life among survivors and relatives, and high resource use both in developed and ...

  • Evaluation of retromolar canals on cone beam computerized tomography scans and digital panoramic radiographs 

    Palma, Luiz Felipe [UNIFESP]; Buck, Ariane Fraga; Kfouri, Flavio de Avila; Blachman, Isaac Tobias; Lombardi, Leonardo Augusto; Cavalli, Marcelo Arthur (Springer Heidelberg, 2017)
    The purpose of this study was to carry out morphologic and topographic analyses of retromolar canals on cone beam computerized tomography (CBCT) scans, comparing findings to others obtained from the corresponding digital ...

  • A comparative study of Ki-67 antigen expression between luminal A and triple-negative subtypes of breast cancer 

    Borges, Umbelina Soares; Costa-Silva, Danylo Rafhael; da Silva-Sampaio, Joao Paulo; Escorcio-Dourado, Carla Solange; Conde, Airton Mendes, Jr.; Campelo, Viriato; Gebrim, Luiz Henrique [UNIFESP]; da Silva, Benedito Borges; Lopes-Costa, Pedro Vitor (Humana Press Inc, 2017)
    Tumor biomarkers such as hormone receptors, HER-2 and Ki-67 are used routinely in clinical practice for classification of molecular subtypes of breast cancer. Cell proliferation evaluated by Ki-67 antigen expression is ...

  • Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level 

    Rhodes, Johanna; Desjardins, Christopher A.; Sykes, Sean M.; Beale, Mathew A.; Vanhove, Mathieu; Sakthikumar, Sharadha; Chen, Yuan; Gujja, Sharvari; Saif, Sakina; Chowdhary, Anuradha; Lawson, Daniel John; Ponzio, Vinicius [UNIFESP]; Colombo, Arnaldo Lopes [UNIFESP]; Meyer, Wieland; Engelthaler, David M.; Hagen, Ferry; Teresa Illnait-Zaragozi, Maria; Alanio, Alexandre; Vreulink, Jo-Marie; Heitman, Joseph; Perfect, John R.; Litvintseva, Anastasia P.; Bicanic, Tihana; Harrison, Thomas S.; Fisher, Matthew C.; Cuomo, Christina A. (Genetics Society America, 2017)
    Cryptococcus neoformans var. grubii is the causative agent of cryptococcal meningitis, a significant source of mortality in immunocompromised individuals, typically human immunodeficiency virus/AIDS patients from developing ...

  • Pancreatic Agenesis due to Compound Heterozygosity for a Novel Enhancer and Truncating Mutation in the PTF1A Gene 

    Gabbay, Monica [UNIFESP]; Ellard, Sian; De Franco, Elisa; Moises, Regina S. [UNIFESP] (Galenos Yayincilik, 2017)
    Neonatal diabetes, defined as the onset of diabetes within the first six months of life, is very rarely caused by pancreatic agenesis. Homozygous truncating mutations in the PTF1A gene, which encodes a transcriptional ...

  • Thalidomide is Associated With Increased T Cell Activation and Inflammation in Antiretroviral-naive HIV-infected Individuals in a Randomised Clinical Trial of Efficacy and Safety 

    Vergara, Tania R. C. [UNIFESP]; Samer, Sadia [UNIFESP]; Santos-Oliveira, Joanna R.; Giron, Leila B. [UNIFESP]; Arif, Muhammad Shoaib [UNIFESP]; Silva-Freitas, Maria Luciana; Cherman, Lia A.; Treitsman, Mauro S.; Chebabo, Alberto; Sucupira, Maria Cecilia A. [UNIFESP]; Da-Cruz, Aldam.; Diaz, Ricardo Sobhie [UNIFESP] (Elsevier Science Bv, 2017)
    Trial Design: Open-label, randomised, controlled, pilot proof-of-concept clinical trial. Methods: Participants: Antiretroviral naive adult males with CD4 count >= 350 cells/mm(3). Interventions: Patients were randomised ...

  • Ciliary Muscle Electrostimulation to Restore Accommodation in Patients With Early Presbyopia: Preliminary Results 

    Gualdi, Luca; Gualdi, Federica; Rusciano, Dario; Ambrosio, Renato, Jr. [UNIFESP]; Salomao, Marcella Q. [UNIFESP]; Lopes, Bernardo [UNIFESP]; Cappello, Veronica; Fintina, Tatiana; Gualdi, Massimo (Slack Inc, 2017)
    PURPOSE: To report short-term results of pulsed ciliary muscle electrostimulation to improve near vision, likely through restoring accommodation in patients with emmetropic presbyopia. METHODS: In a prospective non-randomized ...

  • Relationship between the Nutritional Status of Vitamin A per Trimester of Pregnancy with Maternal Anthropometry and Anemia after Roux-en-Y Gastric Bypass 

    Cruz, Sabrina; Matos, Andrea; da Cruz, Suelem Pereira; Pereira, Silvia; Saboya, Carlos [UNIFESP]; Ramalho, Andrea (Mdpi, 2017)
    The aim of this study was to compare the nutritional status of vitamin A per trimester of pregnancy, as well as to assess its influence on pre-pregnancy BMI, total gestational weight gain (TGWG) and presence of anemia in ...

  • Public security female workers at the coast of Parana, Brazil: intersections of gender, work, violence(s), and health 

    Schneider, Daniele; Signorelli, Marcos Claudio; Gomes Pereira, Pedro Paulo [UNIFESP] (Abrasco, 2017)
    This study aimed to promote visibility of women working in public security along the Parana coast, articulating issues of gender, violence(s), and the health-disease process. The methodology was qualitative, through an ...

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