Now showing items 1-3 of 3

    • Absence of activating mutations in the hot spots of the LH receptor and Gs-alpha genes in Leydig cell tumors 

      Vieira, TCA [UNIFESP]; Cerutti, J. M. [UNIFESP]; Silva, MRD da [UNIFESP]; Delcelo, R. [UNIFESP]; Abucham, J. [UNIFESP] (Editrice Kurtis S R L, 2002-07-01)
      Leydig-cell tumors are functioning endocrine tumors that produce T autonomously leading to isosexual precocity in boys and virilization in female patients. Molecular abnormalities such as activating mutations of the ...
    • Análise dos polimorfismos do KISS1 em meninas com puberdade precoce central 

      Goncalves, Eline Maria Stafuzza [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2013-12-20)
      BACKGROUND: Puberty may be influenced by genetic, nutritional, environmental and socioeconomic factors. However, its etiology is unknown. The influence of the kisspeptin-GPR54 complex in the hypothalamus-pituitary-ovarian ...
    • Evaluation of melatonin on the precocious puberty: a pilot study 

      Holanda, Felisbela Soares de [UNIFESP]; Tufik, Sergio [UNIFESP]; Bignotto, Magda [UNIFESP]; Maganhin, Carla G. [UNIFESP]; Laprano Vieira, Lucia Helena [UNIFESP]; Baracat, Edmund C.; Soares, Jose Maria [UNIFESP] (Informa Healthcare, 2011-08-01)
      Objective. To evaluate the effect of 6-sulphatoxymelatonin on the sleep quality of girls with precocious puberty. Study design. Ninety-nine girls were divided into three groups: GI, precocious puberty; GII, normal prepubescent; ...