Now showing items 1-9 of 9

    • Análise de polimorfismos nos códons 11, 72 e 248 do gene tp53 em mulheres com câncer de mama 

      Almeida, Bruna Cristine de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-02-29)
      We evaluated the association between TP53 gene polymorphisms and Breast Cancer in Brazilian women. Genomic DNA was extracted from peripheral blood cells collected from 393 women. TP53 gene polymorphisms were investigated ...
    • Análise dos polimorfismos do KISS1 em meninas com puberdade precoce central 

      Goncalves, Eline Maria Stafuzza [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2013-12-20)
      BACKGROUND: Puberty may be influenced by genetic, nutritional, environmental and socioeconomic factors. However, its etiology is unknown. The influence of the kisspeptin-GPR54 complex in the hypothalamus-pituitary-ovarian ...
    • Association of endothelial nitric oxide synthase gene intron 4 polymorphism with end-stage renal disease 

      Bellini, Maria H.; Figueira, Marcia N.; Piccoli, Michelly F.; Marumo, Julio T.; Cendoroglo, Maysa S.; Neto, Miguel C.; Dalboni, Maria Aparecida [UNIFESP]; Batista, Marcelo C.; Goes, Miguel A.; Schor, Nestor (Wiley-Blackwell, 2007-06-01)
      Background: Nitric oxide (NO) released from endothelial cells is related to the maintenance of physiological vascular tone. the impairment of endothelial NO generation brought about by gene polymorphism is considered one ...
    • Association study of dopamine D2 and D3 receptor gene polymorphisms with cocaine dependence 

      Messas, G.; Meira-Lima, I; Turchi, M.; Franco, O.; Guindalini, C.; Castelo, A.; Laranjeira, R.; Vallada, H. (Lippincott Williams & Wilkins, 2005-09-01)
      Genetic factors play a role in the vulnerability to cocaine dependence. the reinforcing properties of cocaine are related to the dopaminergic system, and, in particular, the dopamine receptors have been linked to the reward ...
    • Associations between cytokine gene polymorphisms and recurrent pregnancy loss 

      Daher, S.; Shulzhenko, N.; Morgun, A.; Mattar, Rosiane [UNIFESP]; Rampim, G. F.; Camano, L.; DeLima, M. G. (Elsevier B.V., 2003-02-01)
      Since certain cytokines may play a role in unexplained recurrent pregnancy loss (RPL) and also some cytokine gene polymorphisms may affect the level of cytokine production, the aim of the present study was to investigate ...
    • Cytokine genotyping in preeclampsia 

      Daher, S.; Sass, N.; Oliveira, L. G.; Mattar, Rosiane [UNIFESP] (Blackwell Publishing, 2006-02-01)
      ProblemConsidering that cytokines are involved in preeclampsia (PE) pathogenesis and that cytokine gene polymorphism may affect cytokine production, our purpose was to investigate the association of PE with tumor necrosis ...
    • Fc gamma receptor IIIb polymorphism and systemic lupus erythematosus: association with disease susceptibility and identification of a novel FCGR3B*01 variant 

      Santos, Viviane Cardoso dos [UNIFESP]; Grecco, Marcelle [UNIFESP]; Pereira, Kaline Medeiros Costa [UNIFESP]; Terzian, Cláudia Cristina Naufel [UNIFESP]; Andrade, Luiz Eduardo Coelho [UNIFESP]; Silva, Neusa Pereira da [UNIFESP] (Sage Publications Ltd, 2016)
      Objective The objective of this study was to evaluate the association between Fc gamma receptor IIIb polymorphism and susceptibility to systemic lupus erythematosus and clinical traits of the disease. Methods Genomic DNA ...
    • Future perspective for diagnosis in autoimmune diseases 

      Andrade, Luiz Eduardo Coelho [UNIFESP] (Academia Brasileira de Ciências, 2009-09-01)
      Human beings have taken successive approaches for the understanding and management of diseases. Initially brewed in supernatural concepts and mystical procedures, a vigorous scientific approach has emerged on the grounds ...
    • Immunoregulatory gene polymorphisms in women with preeclampsia 

      Pendeloski, Karen P. T. [UNIFESP]; Sass, Nelson [UNIFESP]; Torloni, Maria R. [UNIFESP]; Mattar, Rosiane [UNIFESP]; Moron, Antonio F. [UNIFESP]; Franchim, Camila S. [UNIFESP]; Daher, Silvia [UNIFESP] (Nature Publishing Group, 2011-03-01)
      The costimulatory molecules CD28, cytotoxic T-lymphocyte antigen-4 (CTLA-4) (cytotoxic T-lymphocyte-associated antigen-4) and inducible costimulator (ICOS) are believed to have a critical modulatory role in the immune ...