Now showing items 1-10 of 33

    • Advancing biomarker research: utilizing 'Big Data' approaches for the characterization and prevention of bipolar disorder 

      McIntyre, Roger S.; Cha, Danielle S.; Jerrell, Jeanette M.; Swardfager, Walter; Kim, Rachael D.; Costa, Leonardo G.; Baskaran, Anusha; Soczynska, Joanna K.; Woldeyohannes, Hanna O.; Mansur, Rodrigo B. [UNIFESP]; Brietzke, Elisa [UNIFESP]; Powell, Alissa M.; Gallaugher, Ashley; Kudlow, Paul; Kaidanovich-Beilin, Oksana; Alsuwaidan, Mohammad (Wiley-Blackwell, 2014-08-01)
      Objective: To provide a strategic framework for the prevention of bipolar disorder (BD) that incorporates a 'Big Data' approach to risk assessment for BD.Methods: Computerized databases (e. g., Pubmed, PsychInfo, and ...
    • Analytical approaches for lipidomics and its potential applications in neuropsychiatric disorders 

      Sethi, Sumit [UNIFESP]; Hayashi, Mirian A. [UNIFESP]; Sussulini, Alessandra; Tasic, Ljubica; Brietzke, Elisa [UNIFESP] (Taylor & Francis Ltd, 2017)
      Objectives: In this review, the authors discuss an overview of lipidomics followed by in-depth discussion of its application to the study of human diseases, including extraction methods of lipids, analytical techniques and ...
    • Anti-inflammatory agents in the treatment of bipolar depression: a systematic review and meta-analysis 

      Rosenblat, Joshua D.; Kakar, Ron; Berk, Michael; Kessing, Lars V.; Vinberg, Maj; Baune, Bernhard T.; Mansur, Rodrigo B. [UNIFESP]; Brietzke, Elisa [UNIFESP]; Goldstein, Benjamin I.; McIntyre, Roger S. (Wiley-Blackwell, 2016)
      ObjectiveInflammation has been implicated in the risk, pathophysiology, and progression of mood disorders and, as such, has become a target of interest in the treatment of bipolar disorder (BD). Therefore, the objective ...
    • Apolipoprotein E genotype is not associated with cognitive impairment in older adults with bipolar disorder 

      Kerr, Daniel Shikanai; Stella, Florindo; Radanovic, Marcia; Aprahamian, Ivan; Bertollucci, Paulo Henrique Ferreira [UNIFESP]; Forlenza, Orestes Vicente (Wiley-Blackwell, 2016)
      ObjectivesCognitive decline is part of the long-term outcome for many individuals with bipolar disorder (BD). The epsilon 4 allele (APOE*4) of apolipoprotein E (APOE) is a well-established risk factor for dementia in ...
    • Apolipoprotein E genotype is not associated with cognitive impairment in older adults with bipolar disorder 

      Kerr, Daniel Shikanai; Stella, Florindo; Radanovic, Marcia; Aprahamian, Ivan; Bertollucci, Paulo Henrique Ferreira [UNIFESP]; Forlenza, Orestes Vicente (Wiley-Blackwell, 2016)
      ObjectivesCognitive decline is part of the long-term outcome for many individuals with bipolar disorder (BD). The epsilon 4 allele (APOE*4) of apolipoprotein E (APOE) is a well-established risk factor for dementia in ...
    • BDNF and BMI effects on brain structures of bipolar offspring: results from the global mood and brain science initiative 

      Mansur, R. B.; Brietzke, E. [UNIFESP]; McIntyre, R. S.; Cao, B.; Lee, Y.; Japiassu, L.; Chen, K.; Lu, R.; Lu, W.; Li, T.; Xu, G.; Lin, K. (Wiley, 2017)
      Objective: To compare brain-derived neurotrophic factor (BDNF) levels between offspring of individuals with bipolar disorders (BD) and healthy controls (HCs) and investigate the effects of BDNF levels and body mass index ...
    • Bipolar disorder course, impaired glucose metabolism and antioxidant enzymes activities: A preliminary report 

      Mansur, Rodrigo B. [UNIFESP]; Rizzo, Lucas B. [UNIFESP]; Santos, Camila M. [UNIFESP]; Asevedo, Elson [UNIFESP]; Cunha, Graccielle R. [UNIFESP]; Noto, Mariane N. [UNIFESP]; Pedrini, Mariana [UNIFESP]; Zeni-Graiff, Maiara [UNIFESP]; Gouvea, Eduardo S.; Cordeiro, Quirino; Reininghaus, Eva Z.; McIntyre, Roger S.; Brietzke, Elisa [UNIFESP] (Pergamon-Elsevier Science Ltd, 2016)
      This study aimed to examine the role of oxidative stress in bipolar disorder (BD) by evaluating the relationship among antioxidant enzymes activities, impaired glucose metabolism (IGM) and illness course. We measured the ...
    • Childhood maltreatment and coping in bipolar disorder 

      Daruy-filho, Ledo; Brietzke, Elisa [UNIFESP]; Kluwe-schiavon, Bruno; Fabres, Cristiane Da Silva; Grassi-oliveira, Rodrigo (Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo, 2013-12-01)
      A personal history of childhood maltreatment has been associated with unfavorable outcomes in bipolar disorder (BD). The impact of early life stressors on the course of BD may be influenced by individual differences in ...
    • Dysfunctional family environment in affected versus unaffected offspring of parents with bipolar disorder 

      Ferreira, Guilherme S.; Moreira, Carolina R. L.; Kleinman, Ana; Nader, Edmir C. G. P.; Gomes, Bernardo Carramao; Teixeira, Ana Maria A.; Almeida Rocca, Cristiana C.; Nicoletti, Mark; Soares, Jair C.; Busatto, Geraldo F.; Lafer, Beny; Caetano, Sheila C. (Sage Publications Ltd, 2013-11-01)
      Objective: Children of parents with bipolar disorder (BD) are at heightened risk for developing mood and other psychiatric disorders. We proposed to evaluate the environment of families with at least one parent with BD ...
    • Effects of sodium butyrate in animal models of mania and depression: implications as a new mood stabilizer 

      Resende, Wilson R.; Valvassori, Samira S.; Reus, Gislaine Z.; Varela, Roger B.; Arent, Camila O.; Ribeiro, Karine F.; Bavaresco, Daniela V.; Andersen, Monica L. [UNIFESP]; Zugno, Alexandra I.; Quevedo, Joao (Lippincott Williams & Wilkins, 2013-10-01)
      Bipolar disorder is a severe mood disorder with high morbidity and mortality. Despite adequate treatment, patients continue to have recurrent mood episodes, residual symptoms, and functional impairment. Some preclinical ...