Now showing items 1-10 of 44

    • Absence of DNA damage in multiple organs (blood, liver, kidney, thyroid gland and urinary bladder) after acute fluoride exposure in rats 

      Leite, Aline de Lima; Santiago, Joel Ferreira; Levy, Flavia Mauad; Maria, Andrea Gutierrez; Fernandes, Mileni da Silva; Salvadori, Daisy Maria Favero; Ribeiro, Daniel Araki [UNIFESP]; Rabelo Buzalaf, Marflia Afonso (Sage Publications Ltd, 2007-05-01)
      Fluoride has been widely used in dentistry as a caries prophylactic agent. However, there has been some speculation that excess fluoride could cause an impact on genome integrity. in the current study, the potential DNA ...
    • Acute crack cocaine exposure induces genetic damage in multiple organs of rats 

      Moretti, Eduardo Gregolin [UNIFESP]; Yujra, Veronica Quispe [UNIFESP]; Claudio, Samuel Rangel [UNIFESP]; Silva, Marcelo Jose Dias; Vilegas, Wagner; Pereira, Camilo Dias Seabra [UNIFESP]; De Oliveira, Flavia [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Springer Heidelberg, 2016)
      Crack cocaine is a very toxic product derived from cocaine. The aim of this study was to evaluate genetic damage in multiple organs of rats following acute exposure to crack cocaine. A total of 20 Wistar rats were distributed ...
    • Adolescent varicocele: improved sperm function after varicocelectomy 

      Lacerda, Jose Iran [UNIFESP]; Del Giudice, Paula Toni [UNIFESP]; Silva, Barbara Ferreira da [UNIFESP]; Nichi, Marcilio; Fariello, Roberta Maria [UNIFESP]; Fraietta, Renato [UNIFESP]; Restelli, Adriana Ester [UNIFESP]; Blumer, Camile Garcia [UNIFESP]; Bertolla, Ricardo Pimenta [UNIFESP]; Cedenho, Agnaldo Pereira [UNIFESP] (Elsevier B.V., 2011-03-01)
      Objective: To assess the effect of varicocelectomy on sperm function (DNA integrity and mitochondrial activity) and levels of lipid peroxidation in seminal plasma of adolescents.Design: Prospective study.Setting: Patients ...
    • Analysis of the functional aspects and seminal plasma proteomic profile of sperm from smokers 

      Antoniassi, Mariana Pereira [UNIFESP]; Intasqui, Paula [UNIFESP]; Camargo, Mariana [UNIFESP]; Zylbersztejn, Daniel Suslik [UNIFESP]; Carvalho, Valdemir Melechco; Cardozo, Karina H. M.; Bertolla, Ricardo Pimenta [UNIFESP] (Wiley, 2016)
      Objective To evaluate the effect of smoking on sperm functional quality and seminal plasma proteomic profile. Patients and Methods Sperm functional tests were performed in 20 non-smoking men with normal semen quality, ...
    • Análise morfoquantitativa, da expressão de fatores miogênicos e de mediadores inflamatórios do músculo estriado esquelético distante da lesão térmica por escaldadura em ratos wistar jovens 

      Quintana, Hananiah Tardivo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-02-26)
      Burn injury (BI) is an important epidemiological problem worldwide; those occurring in children have a higher frequency and occurring by outpouring hot liquids, for scalds are among the most common accidents. BI greater ...
    • Antigenotoxicity and antimutagenicity of lycopene in HepG2 cell line evaluated by the comet assay and micronucleus test 

      Scolastici, Clarissa; Lima, Rodrigo Otavio Alves de; Barbisan, Luis Fernando; Ferreira, Ana Lucia dos Anjos; Ribeiro, Daniel Araki [UNIFESP]; Salvadori, Daisy Maria Favero (Elsevier B.V., 2008-03-01)
      Epidemiological studies have provided evidence that high consumption of tomatoes effectively reduces the risk of reactive oxygen species (ROS)-mediated diseases such as cancer. Tomatoes are rich sources of lycopene, a ...
    • Are endogenous sex hormones related to DNA damage in paradoxically sleep-deprived female rats? 

      Andersen, Monica Levy [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Alvarenga, Tathiana Aparecida [UNIFESP]; Silva, Andressa [UNIFESP]; Araujo, Paula [UNIFESP]; Zager, Adriano [UNIFESP]; Tenório, Neuli Maria [UNIFESP]; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2010-02-01)
      The aim of this investigation was to evaluate overall DNA damage induced by experimental paradoxical sleep deprivation (PSD) in estrous-cycling and ovariectomized female rats to examine possible hormonal involvement during ...
    • Association between obesity and alteration of sperm DNA integrity and mitochondrial activity 

      Fariello, Roberta M. [UNIFESP]; Pariz, Juliana R. [UNIFESP]; Spaine, Deborah M. [UNIFESP]; Cedenho, Agnaldo P. [UNIFESP]; Bertolla, Ricardo P. [UNIFESP]; Fraietta, Renato [UNIFESP] (Wiley-Blackwell, 2012-09-01)
      OBJECTIVETo assess the effect of obesity on semen analysis, sperm mitochondrial activity and DNA fragmentation.MATERIALS and METHODSA transversal study of 305 male patients, presenting for clinical evaluation, was carried ...
    • Association between the seminal plasma proteome and sperm functional traits 

      Intasqui, Paula [UNIFESP]; Camargo, Mariana [UNIFESP]; Antoniassi, Mariana Pereira [UNIFESP]; Cedenho, Agnaldo Pereira [UNIFESP]; Carvalho, Valdemir Melechco; Morais Cardozo, Karina Helena; Zylbersztejn, Daniel Suslik [UNIFESP]; Bertolla, Ricardo Pimenta [UNIFESP] (Elsevier Science Inc, 2016)
      Objective: To analyze the seminal plasma proteome and biological functions associated with sperm functional alterations. Design: Cross-sectional study. Setting: University andrology and research laboratories. Patient(s): ...
    • Behavioral and genetic effects promoted by sleep deprivation in rats submitted to pilocarpine-induced status epilepticus 

      Matos, Gabriela [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Alvarenga, Tathiana Aparecida [UNIFESP]; Hirotsu, Camila [UNIFESP]; Scorza, Fulvio Alexandre [UNIFESP]; Le Sueur-Maluf, Luciana [UNIFESP]; Noguti, Juliana [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Tufik, Sergio [UNIFESP]; Andersen, Monica Levy [UNIFESP] (Elsevier B.V., 2012-05-02)
      The interaction between sleep deprivation and epilepsy has been well described in electrophysiological studies, but the mechanisms underlying this association remain unclear. the present study evaluated the effects of sleep ...