Now showing items 1-10 of 18

    • BCG vaccination in patients with severe combined immunodeficiency: Complications, risks, and vaccination policies 

      Marciano, Beatriz E.; Huang, Chiung-Yu; Joshi, Gyan; Rezaei, Nima; Costa-Carvalho, Beatriz Tavares [UNIFESP]; Allwood, Zoe; Ikinciogullari, Aydan; Reda, Shereen M.; Gennery, Andrew; Thon, Vojtech; Espinosa-Rosales, Francisco; Al-Herz, Waleed; Porras, Oscar; Shcherbina, Anna; Szaflarska, Anna; Kilic, Sebnem; Franco, Jose L.; Gomez Raccio, Andrea C.; Roxo, Persio; Esteves, Isabel; Galal, Nermeen; Grumach, Anete Sevciovic; Al-Tamemi, Salem; Yildiran, Alisan; Orellana, Julio C.; Yamada, Masafumi; Morio, Tomohiro; Liberatore, Diana; Ohtsuka, Yoshitoshi; Lau, Yu-Lung; Nishikomori, Ryuta; Torres-Lozano, Carlos; Mazzucchelli, Juliana T. L. [UNIFESP]; Vilela, Maria M. S. [UNIFESP]; Tavares, Fabiola S. [UNIFESP]; Cunha, Luciana; Pinto, Jorge A.; Espinosa-Padilla, Sara E.; Hernandez-Nieto, Leticia; Elfeky, Reem A.; Ariga, Tadashi; Toshio, Heike; Dogu, Figen; Cipe, Funda; Formankova, Renata; Enriqueta Nunez-Nunez, M.; Bezrodnik, Liliana; Marques, Jose Goncalo; Pereira, Maria I.; Listello, Viviana; Slatter, Mary A.; Nademi, Zohreh; Kowalczyk, Danuta; Fleisher, Thomas A.; Davies, Graham; Neven, Benedicte; Rosenzweig, Sergio D. (Elsevier B.V., 2014-04-01)
      Background: Severe combined immunodeficiency (SCID) is a syndrome characterized by profound T-cell deficiency. BCG vaccine is contraindicated in patients with SCID. Because most countries encourage BCG vaccination at birth, ...

    • BmTI antigens induce a bovine protective immune response against Boophilus microplus tick 

      Andreotti, R.; Gomes, A.; Malavazi-Piza, K. C.; Sasaki, S. D.; Sampaio, CAM; Tanaka, A. S. (Elsevier B.V., 2002-03-01)
      Boophilus microplus trypsin inhibitors (BmTIs) present in larvae were preliminarily characterized as active proteins, approximately 10-18 kDa, by SDS-PAGE. BmTIs showed trypsin inhibitory activity on reverse zymography ...

    • Dendritic Cells Primed with Paracoccidioides brasiliensis Peptide P10 Are Therapeutic in Immunosuppressed Mice with Paracoccidioidomycosis 

      Silva, Leandro B. R.; Dias, Lucas S.; Rittner, Glauce M. G.; Munoz, Julian E.; Souza, Ana C. O.; Nosanchuk, Joshua D.; Travassos, Luiz R. [UNIFESP]; Taborda, Carlos P. (Frontiers Media Sa, 2017)
      Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America, with the highest prevalence in Brazil, Colombia, and Venezuela. Fungi of the Paracoccidioides genus are etiologic agents of the disease. The 15 ...

    • Human antibody responses of patients living in endemic areas for schistosomiasis to the tegumental protein Sm29 identified through genomic studies 

      Cardoso, F. C.; Pacifico, RNA; Mortara, Renato Arruda [UNIFESP]; Oliveira, S. C. (Blackwell Publishing, 2006-06-01)
      Surface proteins of schistosomes are exposed to host tissues and thus present as potential candidate molecules for the development of new intervention strategies. Herein, we have identified a new tegumental protein of ...

    • Humoral immune response after genetic immunization is consistently improved by electroporation 

      Parise, Carolina Bellini [UNIFESP]; Lisboa, Bianca [UNIFESP]; Takeshita, Daniela [UNIFESP]; Sacramento, Chester Bittencourt [UNIFESP]; Moraes, Jane Zveiter de [UNIFESP]; Han, Sang Won [UNIFESP] (Elsevier B.V., 2008-07-23)
      Aiming to evaluate some parameters to influence the immune response to DNA vaccination, we compare three protocols of DNA immunization (i.m. injections, i.m. injections followed by electroporation, and the effect of i.p. ...

    • Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients 

      Fonseca, Simone G.; Coutinho-Silva, Adriana; Fonseca, Luiz Augusto M.; Segurado, Aluisio C.; Moraes, Sandra L.; Rodrigues, Helcio; Hammer, Juergen; Kallas, Esper Georges [UNIFESP]; Sidney, John; Sette, Alessandro; Kalil, Jorge; Cunha-Neto, Edecio (Lippincott Williams & Wilkins, 2006-11-28)
      Objective: To identify promiscuous and potentially protective human CD4 T-cell epitopes in most conserved regions within the protein-coding genome of HIV-1 clade B consensus sequence.Design: We used the TEPITOPE algorithm ...

    • Immune response and tolerability of varicella vaccine in children and adolescents with systemic lupus erythematosus previously exposed to varicella-zoster virus 

      Barbosa, Cassia Maria Passarelli Lupoli [UNIFESP]; Terreri, Maria Teresa Ramos Ascensão [UNIFESP]; Rosario, P. O. [UNIFESP]; Moraes-Pinto, Maria Isabel de [UNIFESP]; Silva, C. A. A.; Hilário, Maria Odete Esteves [UNIFESP] (Clinical & Exper Rheumatology, 2012-09-01)
      ObjectivesThe aim of the present paper is to evaluate the immune response and tolerability of varicella vaccine in children and adolescents with systemic lupus erythematosus previously exposed to varicella-zoster virus.MethodsWe ...

    • Immunology of canine leishmaniasis 

      Barbiéri, Clara Lúcia [UNIFESP] (Blackwell Publishing, 2006-07-01)
      The role of dogs as the main reservoir of visceral leishmaniasis has led to an increased interest in the immune responses and in Leishmania antigens implicated in protective cellular immunity in canine visceral leishmaniasis. ...

    • Importance of CD8 T cell-mediated immune response during intracellular parasitic infections and its implications for the development of effective vaccines 

      Rodrigues, Mauricio Martins [UNIFESP]; Boscardin, Silvia Beatriz [UNIFESP]; Vasconcelos, Jose Ronnie Carvalho de [UNIFESP]; Hiyane, Meire Ioshie [UNIFESP]; Salay, Gerson [UNIFESP]; Soares, Irene S. (Academia Brasileira de Ciências, 2003-12-01)
      Obligatory intracellular parasites such as Plasmodium sp, Trypanosoma cruzi, Toxoplasma gondii and Leishmania sp are responsible for the infection of hundreds of millions of individuals every year. These parasites can ...

    • Linear epitopes of Paracoccidioides brasiliensis and Other Fungal Agents of Human Systemic Mycoses As vaccine Candidates 

      Travassos, Luiz R. [UNIFESP]; Taborda, Carlos P. [UNIFESP] (Frontiers Media Sa, 2017)
      Dimorphic fungi are agents of systemic mycoses associated with significant morbidity and frequent lethality in the Americas. Among the pathogenic species are Paracoccidioides brasiliensis and Paracoccidioides lutzii, which ...