Now showing items 1-3 of 3

    • Aerobic exercise training rescues protein quality control disruption on white skeletal muscle induced by chronic kidney disease in rats 

      Almeida Monteiro De Moraes, Wilson Max [UNIFESP]; Moraes de Souza, Pamella Ramona; da Paixao, Nathalie Alves; Oliveira de Sousa, Luis Gustavo; Ribeiro, Daniel Araki [UNIFESP]; Marshall, Andrea G.; Prestes, Jonato; Irigoyen, Maria Claudia; Brum, Patricia Chakur; Medeiros, Alessandra [UNIFESP] (Wiley, 2018)
      We tested whether aerobic exercise training (AET) would modulate the skeletal muscle protein quality control (PQC) in a model of chronic kidney disease (CKD) in rats. Adult Wistar rats were evaluated in four groups: control ...

    • Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma 

      Pereira Eugenio, Angela Isabel [UNIFESP]; Fook-Alves, Veruska Lia [UNIFESP]; de Oliveira, Mariana Bleker [UNIFESP]; Fernando, Rodrigo Carlini [UNIFESP]; Zanatta, Daniela B.; Strauss, Bryan Eric; Regis Silva, Maria Regina [UNIFESP]; Porcionatto, Marimelia Aparecida [UNIFESP]; Braga Colleoni, Gisele Wally [UNIFESP] (Impact Journals Llc, 2017)
      HSP70 connects multiple signaling pathways that work synergistically to protect tumor cells from death by proteotoxic stress and represents a possible target to establish a new approach for multiple myeloma treatment. ...

    • UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression 

      Bromati, Carla R.; Lellis-Santos, Camilo; Yamanaka, Tatiana S.; Nogueira, Tatiane C. A.; Leonelli, Mauro; Caperuto, Luciana C. [UNIFESP]; Gorjao, Renata; Leite, Adriana R.; Anhe, Gabriel F.; Bordin, Silvana (Amer Physiological Soc, 2011-01-01)
      Bromati CR, Lellis-Santos C, Yamanaka TS, Nogueira TC, Leonelli M, Caperuto LC, Gorjao R, Leite AR, Anhe GF, Bordin S. UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT ...