Browsing by Subject "type 2 diabetes mellitus"

Now showing items 1-10 of 10

    • ADIPOQ and adiponectin: the common ground of hyperglycemia and coronary artery disease? 

      Oliveira, Carolina Soares Viana de [UNIFESP]; Giuffrida, Fernando M. A. [UNIFESP]; Crispim, Felipe [UNIFESP]; Saddi-rosa, Pedro [UNIFESP]; Reis, André Fernandes [UNIFESP] (Sociedade Brasileira de Endocrinologia e Metabologia, 2011-10-01)
      Plasma adiponectin and the coding gene for adiponectin, ADIPOQ, are thought to explain part of the interaction between obesity, insulin resistance, type 2 diabetes (T2DM) and coronary artery disease (CAD). Here, we illustrate ...

    • Diabetes melito do tipo 2 na infância e adolescência: revisão da literatura 

      Gabbay, Monica Andrade Lima [UNIFESP]; Cesarini, Paulo R. [UNIFESP]; Dib, Sergio Atala [UNIFESP] (Sociedade Brasileira de Pediatria, 2003-06-01)
      OBJECTIVE: the objective of this manuscript was to perform a critical review of epidemiology, pathophysiology, diagnosis e treatment of T2DM in youth. SOURCES OF DATA: this review is based on the relevant literature ...

    • Diabetic Hypertensive Leptin Receptor-Deficient db/db Mice Develop Cardioregulatory Autonomic Dysfunction 

      Goncalves, Andrey C. da Costa; Tank, Jens; Diedrich, Andre; Hilzendeger, Aline Mourão [UNIFESP]; Plehm, Ralph; Bader, Michael [UNIFESP]; Luft, Friedrich C.; Jordan, Jens; Gross, Volkmar (Lippincott Williams & Wilkins, 2009-02-01)
      Leptin receptor-deficient db/db mice develop human type 2 diabetes mellitus, hypertension, and obesity with disrupted circadian blood pressure (BP) rhythm. Whether leptin is the sole mechanism mediating autonomic imbalance ...

    • Efetividade e segurança dos fibratos no diabetes mellitus tipo 2: protocolo de revisão sistemática 

      Bonates, Milla Canicali [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-09-24)
      Introduction: The type 2 diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Type 2 diabetes is the predominant form of ...

    • Effect of blood glucose on left ventricular mass in patients with hypertension and type 2 diabetes mellitus 

      Felicio, João S.; Ferreira, Sandra RG; Plavnik, Frida L.; Moises, Valdir; Kohlmann Junior, Oswaldo; Ribeiro, Artur B.; Zannella, Maria Teresa (Elsevier B.V., 2000-11-01)
      The aim of our prospective study was to evaluate the influence of blood glucose (BG) on left ventricular mass and diastolic function in patients with hypertension and type 2 diabetes mellitus (DM). Fifty-six hypertensive ...

    • Laparoscopic treatment of type 2 diabetes mellitus for patients with a body mass index less than 35 

      DePaula, A. L.; Macedo, A. L. V.; Rassi, N.; Machado, C. A.; Schraibman, V. [UNIFESP]; Silva, L. Q.; Halpern, A. (Springer, 2008-03-01)
      Background Type 2 diabetes mellitus (T2DM) is a common disease with numerous complications. Bariatric surgery is an efficient procedure for controlling T2DM in morbidly obese patients. in T2DM, the incretin effect is either ...

    • Metabolic and haemodynamic effects of metformin in patients with type 2 diabetes mellitus and hypertension 

      Uehara, M. H.; Kohlmann, NEB; Zanella, M. T.; Ferreira, SRG (Blackwell Science Ltd, 2001-10-01)
      Background: Since metformin improves insulin sensitivity, it has been indicated for patients with diabetes and hypertension, which are insulin-resistant conditions. in contrast to its well-known effects on carbohydrate ...

    • A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes 

      Reis, A. F.; Dubois-Laforgue, D.; Bellanne-Chantelot, C.; Timsit, J.; Velho, G. (Elsevier B.V., 2004-08-01)
      A G/A single nucleotide polymorphism (SNP) in the position -866 of the UCP2 promoter modulates UCP2 expression in adipose tissue and pancreatic beta-cell, and is associated with variations of body mass index (BMI) and ...

    • The role of angiotensin II antagonism in type 2 diabetes mellitus: A review of renoprotection studies 

      Zanella, Maria Teresa [UNIFESP]; Ribeiro, Artur B. [UNIFESP] (Excerpta Medica Inc, 2002-07-01)
      Background: Diabetic nephropathy is the leading cause of end-stage renal disease (ESRD) in Western and Asian countries. Effective antihypertensive therapy reduces the rate of decline in renal function and postpones ESRD ...

    • Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks 

      Chacra, Antonio R. [UNIFESP]; Tan, Gerry H.; Ravichandran, Shoba; List, James; Chen, Roland; CV181040 Investigators (Sage Publications Ltd, 2011-04-01)
      To assess the long-term efficacy and safety of saxagliptin in patients with type 2 diabetes mellitus inadequately controlled on sulphonylurea monotherapy, 768 patients were randomised to saxagliptin 2.5 or 5 mg in combination ...