Browsing by Subject "trypomastigotes"
Now showing items 1-6 of 6
-
A century of research: what have we learned about the interaction of Trypanosoma cruzi with host cells?
(Instituto Oswaldo Cruz, Ministério da Saúde, 2009-07-01)Since the discovery of Trypanosoma cruzi and the brilliant description of the then-referred to new tripanosomiasis by Carlos Chagas 100 years ago, a great deal of scientific effort and curiosity has been devoted to ...
-
Invasion of MDCK epithelial cells with altered expression of Rho GTPases by Trypanosoma cruzi amastigotes and metacyclic trypomastigotes of strains from the two major phylogenetic lineages
(Elsevier B.V., 2004-04-01)In order to invade mammalian cells, Trypanosoma cruzi infective forms cause distinct rearrangements of membrane and host cell cytoskeletal components. Rho GTPases have been shown to regulate three separate signal transduction ...
-
Mammalian cell invasion and intracellular trafficking by Trypanosoma cruzi infective forms
(Academia Brasileira de Ciências, 2005-03-01)Trypanosoma cruzi, the etiological agent of Chagas disease, occurs as different strains or isolates that may be grouped in two major phylogenetic lineages: T. cruzi I, associated with the sylvatic cycle and T. cruzi II, ...
-
Molecular basis of mammalian cell invasion by Trypanosoma cruzi
(Academia Brasileira de Ciências, 2006-03-01)Establishment of infection by Trypanosoma cruzi, the agent of Chagas' disease, depends on a series of events involving interactions of diverse parasite molecules with host components. Here we focus on the mechanisms of ...
-
Polyclonal B-cell activation by Neisseria meningitidis capsular polysaccharides elicit antibodies protective against Trypanosoma cruzi infection in vitro
(Wiley-Blackwell, 1996-01-01)A hyperimmune rabbit antiserum against group C Neisseria meningitidis agglutinated and lysed Trypanosoma cruzi metacyclic trypomastigotes in a complement-mediated reaction. Immunization of rabbits with the purified ...
-
Trypanosoma cruzi: Effect of protein kinase inhibitors and cytoskeletal protein organization and expression on host cell invasion by amastigotes and metacyclic trypomastigotes
(Academic Press Inc, 1998-09-01)Although trypomastigotes are regarded as the classic infective forms of T. cruzi, amastigotes generated extracellularly or released from infected cells during lysis may circulate and infect other cells. We have compared ...
