Browsing by Subject "tissue kallikrein"

Now showing items 1-7 of 7

    • Action of Bauhinia bauhinioides synthetic peptides on serine proteinases 

      Cagliari, C. I.; De Caroli, F. P.; Nakahata, A. M.; Araujo, M. S.; Nakaie, C. R.; Sampaio, M. U.; Sampaio, CAM; Oliva, MLV (Elsevier B.V., 2003-11-07)
      The kallikrein inhibitor found in Bauhinia bauhinioides seeds (BbKI) differs from classical Kunitz plant inhibitors in the lack of disulfide bridges in its structure [Biochim. Biophys. Acta 1477 (2000) 64-74]. in this ...

    • Chondroitin sulfate and kallikrein in saliva: Markers for glossodynia 

      Loeb, L. M. [UNIFESP]; Naffah-Mazzacoratti, M. G. [UNIFESP]; Porcionatto, M. A. [UNIFESP]; Martins, J. R. M. [UNIFESP]; Kouyoumdjian, M. [UNIFESP]; Weckx, L. M. [UNIFESP]; Nader, H. B. [UNIFESP] (Elsevier B.V., 2008-07-01)
      Glossodynia or burning mouth syndrome is a multifunctional disorder. the oral mucosa is apparently normal but patients report burning and dried mouth and painful tongue and lips. the present study reports biochemical and ...

    • Human plasma kallikrein and tissue kallikrein binding to a substrate based on the reactive site of a factor Xa inhibitor isolated from Bauhinia ungulata seeds 

      Oliva, MLV; Andrade, S.; Batista, IFC; Sampaio, M. U.; Juliano, M.; Fritz, H.; Auerswald, E. A.; Sampaio, CAM (Elsevier B.V., 1999-12-01)
      Kunitz type Bauhinia ungulata factor Xa inhibitor (BuXI) was purified from B. ungulata seeds. BuXI inactivates factor Xa and human plasma kallikrein (HuPK) with K-i values of 18.4 and 6.9 nM, respectively. However, Bauhinia ...

    • Hydrolysis by plasma kallikrein of fluorogenic peptides derived from prorenin processing site 

      Almeida, P. C.; Chagas, JR; Cezari, MHS; Juliano, M. A.; Juliano, L. (Elsevier B.V., 2000-06-15)
      Human plasma kallikrein (HPK) activates plasma prorenin to renin, and the physiological significance of this activation is still unknown. in this paper we investigated the efficiency and the cleavage pattern of the hydrolysis ...

    • Kininogen-derived fluorogenic substrates for investigating the vasoactive properties of rat tissue kallikreins - Identification of a T-kinin-releasing rat kallikrein 

      ElMoujahed, A.; BrillardBourdet, M.; Juliano, M. A.; Moreau, T.; Chagas, JR; Gutman, N.; Prado, E. S.; Gauthier, F. (Springer, 1997-07-15)
      Peptide substrates with intramolecularly quenched fluorescence that reproduce the rat kininogen sequences at both ends of the bradykinin moiety were synthesized and used to investigate the kinin-releasing properties of ...

    • Pharmacological characterization of novel tissue kallikrein inhibitors in vivo 

      Bizeto, L.; Antunes, E.; Portaro, FCV; Juliano, M. A.; Juliano, L.; Prado, E. S.; deNucci, G. (Elsevier B.V., 1996-05-01)
      In this study we have investigated the effect of novel tissue kallikreins on the plasma protein exudation induced by porcine pancreatic kallikrein (PPK) in the rabbit skin in vivo. the tissue kallikrein inhibitors here ...

    • Purification and characterization of active recombinant rat kallikrein rK9 

      Zani, M. L.; Brillard-Bourdet, M.; Lazure, C.; Juliano, L.; Courty, Y.; Gauthier, F.; Moreau, T. (Elsevier B.V., 2001-06-11)
      The rat tissue kallikrein rK9 is most abundant in the submandibular gland and the prostate. It has been successfully expressed in the Pichia pastoris yeast expression system. A full-length cDNA coding for the mature rK9 ...