Browsing by Subject "testis"
Now showing items 1-10 of 22
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Alterations of spermatogenesis in etoposide-treated rats: A stereological study
(Interciencia, 2002-05-01)The etoposide is an anticancer drug that interacts with topoisomerase II. Thirty-day-old rats received intraperitonially 2mg/kg of etoposide for 30 consecutive days. Their testes were analyzed in the adult phase under light ...
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Amifostine protective effect on cisplatin-treated rat testis
(Wiley-Blackwell, 2008-07-01)Cisplatin is a potent drug used in clinical oncology but causes spermatogenesis damage. Amifostine is a drug used against toxicity caused by ionizing irradiation and chemotherapeutic drugs. Since cisplatin provokes fertility ...
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Androgens and the male reproductive tract: an overview of classical roles and current perspectives
(Sociedade Brasileira de Endocrinologia e Metabologia, 2009-11-01)Androgens are steroid hormones that play key roles in the development and maintenance of male phenotype and reproductive function. These hormones also affect the function of several non-reproductive organs, such as bone ...
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Apoptosis and testicular alterations in albino rats treated with etoposide during the prepubertal phase
(Wiley-Blackwell, 2004-07-01)Etoposide is a podophyllotoxin semiderivative that is used in a variety of chemotherapy treatments, including therapy for children tumors. This drug promotes the formation of a ternary DNA-topoisomerase II-etoposide complex ...
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Avaliação do tratamento crônico com resveratrol sobre níveis glicêmicos e parâmetros reprodutivos de ratos com diabetes tipo 1 induzida pela estreptozotocina na pré-puberdade
(Universidade Federal de São Paulo (UNIFESP), 2014-12-18)Aims/hypothesis: In Diabetes Mellitus, the persistent hyperglycemia unleashes the progression of several complications including the overproduction of reactive oxygen species and reproductive alterations. Resveratrol (RES) ...
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Avaliação reprodutiva tardia da prole exposta à nicotina durante as fases de prenhez e lactação
(Universidade Federal de São Paulo (UNIFESP), 2014-07-30)Introduction: About 1/3 of the population smokes. The nicotine found in cigarettes, reaches breast milk and crosses the placental membrane. Previously, it was observed that nicotine administered to female rats during ...
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Can selective retroperitoneal lymphadenectomy be better than unilateral retroperitoneal lymphadenectomy?
(Sociedade Brasileira de Urologia, 2003-10-01)OBJECTIVE: To propose a new modality of retroperitoneal lymphadenectomy as a complementary treatment for patients with high risk, stage I nonseminomatous testicular tumor. MATERIALS AND METHODS: We studied 76 patients with ...
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Carbamazepine damage to rat spermatogenesis in different sexual developmental phases
(Wiley-Blackwell, 2009-10-01)P>Carbamazepine (CBZ) is a first-line antiepileptic drug (AED), although it is also utilized for treatment of psychiatric disorders and neuropathic pain. the utilization of CBZ has been associated with damage to male ...
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Clinical Outcome of Intracytoplasmic Sperm Injection in Infertile Men With Treated and Untreated Clinical Varicocele
(Elsevier B.V., 2010-10-01)Purpose: We evaluated the impact of varicocelectomy on intracytoplasmic sperm injection outcomes in infertile men with clinical varicocele.Materials and Methods: We studied 242 infertile men with a history of clinical ...
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Differential expression and antibacterial activity of epididymis protein 2 isoforms in the male reproductive tract of human and rhesus monkey (Macaca mulatta)
(Soc Study Reproduction, 2004-11-01)The epididymis protein 2 (EP2) gene, the fusion of two ancestral P-defensin genes, is highly expressed in the epididymis and subject to species-specific regulation at the levels of promoter selection, transcription, and ...
