Browsing by Subject "tardive dyskinesia"

Now showing items 1-10 of 12

    • Atypical antipsychotic drugs and tardive dyskinesia: relevance of D-2 receptor affinity 

      Bressan, R. A.; Jones, H. M.; Pilowsky, L. S. (Sage Publications Ltd, 2004-03-01)
      Evidence suggests atypical antipsychotic treatment is associated with a Lower incidence of tardive dyskinesia (TD) than typical antipsychotic drugs, and is a potential antidyskinetic treatment. We present the case of a ...

    • Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats 

      Peres, Fernanda Fiel [UNIFESP]; Leyin, Raquel [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Gouvea, Douglas Albuquerque [UNIFESP]; Almeida, Valeria [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Lungato, Lisandro [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E. C.; Crippa, Jose A.; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena da [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Media Sa, 2016)
      Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's disease patients, CBD is able to attenuate ...

    • Concomitant development of oral dyskinesia and memory deficits in reserpine-treated male and female mice 

      Silva, R. H.; Abilio, V. C.; Torres-Leite, D.; Bergamo, M.; Chinen, C. C.; Claro, F. T.; Carvalho, R. D.; Frussa, R. (Elsevier B.V., 2002-05-14)
      It has been suggested that reserpine-induced oral dyskinesia in rats may provide a new animal model of tardive dyskinesia. Both cognitive deficits and gender have been associated with the development of tardive dyskinesia. ...

    • Effects of baclofen on reserpine-induced vacuous chewing movements in mice 

      Castro, JPMV; Frussa-Filho, R.; Fukushiro, D. F.; Silva, R. H.; Medrano, W. A.; Ribeiro, R. D.; Abilio, V. C. (Elsevier B.V., 2006-02-15)
      We have described that GABA mimetic drugs present the ability to inhibit the expression of reserpine-induced oral movements. in this respect, oral movements is associated with important neuropathologies. This study ...

    • Effects of buspirone on an animal model of tardive dyskinesia 

      Queiroz, Claudio MT [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 1999-11-01)
      1. the effects of buspirone were studied on an animal model of tardive dyskinesia, i.e., the quantification of orofacial dyskinesia in rats repeatedly treated with reserpine.2. Rats were co-treated with saline [SAL] or ...

    • Effects of monosialoganglioside on a new model of tardive dyskinesia 

      Vital, MABF; Frussa-Filho, Roberto [UNIFESP]; Palermo Neto, J. (Elsevier B.V., 1997-10-01)
      1- the effects of monosialoganglioside GM(1) were studied on a new model of tardive dyskinesia, i.e., the frequency of spontaneous tongue protrusions in rats repeatedly treated with reserpine.2- Rats were co-treated with ...

    • Effects of valproic acid on an animal model of tardive dyskinesia 

      Peixoto, M. F.; Abilio, V. C.; Silva, R. H.; Frussa, R. (Elsevier B.V., 2003-06-16)
      GABAergic hypofunction in the basal ganglia is stated as an important mechanism underlying the pathophysiology of tardive dyskinesia. the present study investigates the effects of the GABA-mimetic drug valproic acid (VA) ...

    • The mitochondrial toxin 3-nitropropionic acid aggravates reserpine-induced oral dyskinesia in rats 

      Calvente, Patricia RV [UNIFESP]; Araujo, Carlos CS [UNIFESP]; Bergamo, Marcelo [UNIFESP]; Abilio, Vanessa C. [UNIFESP]; D'Almeida, Vânia [UNIFESP]; Ribeiro, Rosana de A [UNIFESP]; Frussa Filho, Roberto [UNIFESP] (Elsevier B.V., 2002-02-01)
      The effects of a previous long-term administration of the mitochondrial toxin 3-nitropropionic acid were studied on an animal model of tardive dyskinesia, i.e., die frequency of spontaneous tongue protrusions in rats ...

    • Monosialoganglioside (GM(1)) attenuates the behavioural effects of longterm haloperidol administration in supersensitive rats 

      Perry, J. C.; Vital, MABF; Frussa-Filho, R.; Tufik, S.; Palermo-Neto, J. (Elsevier B.V., 2004-03-01)
      In the present study we investigated the effects of co-administration of GM(1) (15.0 mg/kg, twice daily, for 30 days) and haloperidol (1.0 mg/kg, twice daily, for 30 days), as well as the effects of a 5-day treatment with ...

    • Reserpine does not induce orofacial dyskinesia in spontaneously hypertensive rats 

      Queiroz, CMT; Piovezan, R. D.; Frussa-Filho, R. (Elsevier B.V., 1998-09-04)
      The nigrostriatal dopaminergic system seems to be involved in both reserpine-induced orofacial dyskinesia in normal rats and in the pathogenesis of hypertension in spontaneously hypertensive rats. in the present study, ...