Now showing items 1-10 of 10

    • Cotrimoxazole enhances the in vitro susceptibility of Coccidioides posadasii to antifungals 

      Cordeiro, Rossana de Aguiar; Astete-Medrano, Delia Jessica; Marques, Francisca Jakelyne de Farias; Andrade, Heuziwanne Tavares Leite; Perdigão Neto, Lauro Vieira; Tavares, Juliane Lira; Lima, Rita Amanda Chaves de; Patoilo, Kharla Kharolyni Nobre Rabelo; Monteiro, Andre Jalles; Brilhante, Raimunda Sâmia Nogueira; Rocha, Marcos Fábio Gadelha; Camargo, Zoilo Pires de [UNIFESP]; Sidrim, José Júlio Costa (Instituto Oswaldo Cruz, Ministério da Saúde, 2011-12-01)
      The aim of the present study was to evaluate the effect of cotrimoxazole on the in vitro susceptibility of Coccidioides posadasii strains to antifungals. A total of 18 strains of C. posadasii isolated in Brazil were evaluated ...

    • E Test: a novel technique for antimicrobial susceptibility testing 

      Sader, Helio Silva [UNIFESP]; Pignatari, Antonio Carlos Campos [UNIFESP] (Associação Paulista de Medicina - APM, 1994-12-01)
      We describe the applicability of the E test (AB Biodisk Solna, Sweden), a new method for determining minimum inhibitory concentrations of antimicrobial agents against bacteria. This report is based on the literature review ...

    • Evaluation of the in vitro activity of daptomycin against 19615 clinical isolates of Gram-positive cocci collected in North American hospitals (2002-2005) 

      Pfaller, Michael A.; Sader, Helio S.; Jones, Ronald N. (Elsevier B.V., 2007-04-01)
      We evaluated the antimicrobial activity of daptomycin against 19 615 clinical strains consecutively collected by numerous centers located across the United States and Canada (2002-2005). Daptomycin was very active against ...

    • The HIV aspartyl protease inhibitor ritonavir impairs planktonic growth, biofilm formation and proteolytic activity in Trichosporon spp 

      Cordeiro, Rossana de Aguiar; Serpa, Rosana; Leite Mendes, Patricia Bruna; de Jesus Evangelista, Antonio Jose; Colares Andrade, Ana Raquel; Franco, Jonatas da Silva; Pereira, Vandbergue dos Santos; de Alencar, Lucas Pereira; de Oliveira, Jonathas Sales; de Camargo, Zoilo Pires [UNIFESP]; de Lima Neto, Reginaldo Goncalves; Collares Maia Castelo-Branco, Debora de Souza; Nogueira Brilhante, Raimunda Samia; Gadelha Rocha, Marcos Fabio; Costa Sidrim, Jose Julio (Taylor & Francis Ltd, 2017)
      This study evaluated the effect of the protease inhibitor ritonavir (RIT) on Trichosporon asahii and Trichosporon inkin. Susceptibility to RIT was assessed by the broth microdilution assay and the effect of RIT on protease ...

    • Immunity and hypersensitivity to gp43 antigen in susceptible and resistant mice infected with Paracoccidioides brasiliensis 

      Godoy, L. C.; Mariano, M.; Lopes, J. D. (Taylor & Francis Ltd, 2003-10-01)
      Pathogenic mechanisms underlying paracoccidioidomycosis are still poorly understood. A well-established murine model of resistance (mouse lineage A/Sn) and susceptibility (lineage B10.A) to P brasiliensis pulmonary infection ...

    • Impact of thymidylate synthase promoter and DNA repair gene polymorphisms on susceptibility to childhood acute lymphoblastic leukemia 

      Canalle, Renata; Silveira, Vanessa S.; Scrideli, Carlos Alberto; Queiroz, Rosane G. P.; Lopes, Luiz Fernando; Tone, Luiz Gonzaga (Informa Healthcare, 2011-06-01)
      The aim of this study was to evaluate the frequency of polymorphisms in the TYMS, XRCC1, and ERCC2 DNA repair genes in pediatric patients with acute lymphoblastic leukemia using polymerase chain reaction (PCR) and ...

    • Melanin as a virulence factor of Paracoccidioides brasiliensis and other dimorphic pathogenic fungi: a minireview 

      Taborda, Carlos Pelleschi [UNIFESP]; Silva, Marcelo Barbosa da; Nosanchuk, Joshua Daniel; Travassos, Luiz Rodolpho [UNIFESP] (Springer, 2008-04-01)
      Melanin pigments are substances produced by a broad variety of pathogenic microorganisms, including bacteria, fungi, and helminths. Microbes predominantly produce melanin pigment via tyrosinases, laccases, catecholases, ...

    • Prevalence rates and antifungal susceptibility profiles of the Candida parapsilosis species complex: results from a nationwide surveillance of candidaemia in Brazil 

      Goncalves, S. S.; Amorim, C. S.; Nucci, M.; Padovan, Ana Carolina Barbosa [UNIFESP]; Briones, Marcelo Ribeiro da Silva [UNIFESP]; Melo, A. S. A.; Colombo, Arnaldo Lopes [UNIFESP] (Wiley-Blackwell, 2010-07-01)
      P>The genetically heterogeneous taxon Candida parapsilosis was recently reclassified into three species: Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis. the prevalences of these species among 141 ...

    • Selection of a surrogate beta-lactam testing agent for initial susceptibility testing of doripenem, a new carbapenem 

      Jones, Ronald N.; Sader, Helio S. [UNIFESP]; Fritsche, Thomas R.; Janechek, Michael J. (Elsevier B.V., 2007-12-01)
      Doripenem, a broad-spectrum parenteral carbapenem, has potency and pharmacokinetic/pharmacodynamic features most similar to imipenem and meropenem. Because of potential delays in release of commercial testing devices ...

    • Sex-related differences in COPD in five Latin American cities: the PLATINO study 

      Lopez Varela, M. V.; Montes de Oca, M.; Halbert, R. J.; Muino, A.; Perez-Padilla, R.; Talamo, C.; Jardim, Jose Roberto [UNIFESP]; Valdivia, G.; Pertuze, J.; Moreno, D.; Menezes, Ana Maria Baptista [UNIFESP]; PLATINO Team (European Respiratory Soc Journals Ltd, 2010-11-01)
      There is evidence to suggest sex differences exists in chronic obstructive pulmonary disease (COPD) clinical expression. We investigated sex differences in health status perception, dyspnoea and physical activity, and ...