Now showing items 1-6 of 6

    • Antiplasmodial activity study of angiotensin II via Ala scan analogs 

      Silva, Adriana Farias; Bastos, Erick Leite; Torres, Marcelo Der Torossian; Costa-da-Silva, Andre Luis; Ioshino, Rafaella Sayuri; Capurro, Margareth Lara; Alves, Flavio Lopes [UNIFESP]; Miranda, Antonio [UNIFESP]; Fischer Vieira, Renata de Freitas [UNIFESP]; Oliveira, Vani Xavier (Wiley-Blackwell, 2014-08-01)
      Angiotensin II (AII) as well as analog peptides shows antimalarial activity against Plasmodium gallinaceum and Plasmodium falciparum, but the exact mechanism of action is still unknown. This work presents the solid-phase ...

    • Divalent metal requirements for catalysis and stability of the RNA triphosphatase from Trypanosoma cruzi 

      Kikuti, Carlos Massayuki; Tersariol, Ivarne Luis S.; Schenkman, Sergio (Elsevier B.V., 2006-11-01)
      RNA triphosphatases act in the first step of the mRNA capping process, removing the gamma-phosphoryl group from the 5' end of nascent RNA. A metal-dependent catalysis is found in the enzymes from trypanosomes and several ...

    • Innovative low temperature plasma approach for deposition of alumina films 

      Battaglin, Felipe Augusto Darriba; Hosokawa, Ricardo Shindi; Cruz, Nilson Cristino Da; Caseli, Luciano [UNIFESP]; Rangel, Elidiane Cipriano; Silva, Tiago Fiorini Da; Tabacniks, Manfredo Harri (ABM, ABC, ABPol, 2014-12-01)
      Alumina films were deposited from a new plasma method using aluminum acetylacetonate (AAA) powder as precursor. The AAA was sputtered in argon and oxygen plasma mixtures. It was investigated the effect of the oxygen ...

    • A minor beta-structured conformation is the active state of a fusion peptide of vesicular stomatitis virus glycoprotein 

      Sarzedas, Carolina G.; Lima, Carla S.; Juliano, Maria A. [UNIFESP]; Juliano, Luiz [UNIFESP]; Valente, Ana Paula; Da Poian, Andrea T.; Almeida, Fabio C. L. (Wiley-Blackwell, 2008-04-01)
      Entry of enveloped animal viruses into their host cells always depends on a step of membrane fusion triggered by conformational changes in viral envelope glycoproteins. Vesicular stomatitis virus (VSV) infection is mediated ...

    • Molecular modeling of the human eukaryotic translation initiation factor 5A (eIF5A) based on spectroscopic and computational analyses 

      Costa-Neto, Claudio M.; Parreiras-e-Silva, Lucas T.; Ruller, Roberto; Oliveira, Eduardo B.; Miranda, Antonio; Oliveira, Laerte; Ward, Richard J. (Elsevier B.V., 2006-09-01)
      The eukaryotic translation initiation factor 5A (eIF5A) is a protein ubiquitously present in archaea and eukarya, which undergoes a unique two-step post-translational modification called hypusination. Several studies have ...

    • A novel heparan sulphate with high degree of N-sulphation and high heparin cofactor-II activity from the brine shrimp Artemia franciscana 

      Chavante, S. F.; Santos, E. A.; Oliveira, F. W.; Guerrini, M.; Torri, G.; Casu, B.; Dietrich, C. P.; Nader, H. B. (Elsevier B.V., 2000-03-16)
      With the aid of heparinase and heparitinases from Flavobacterium heparinum and C-13 and H-I NMR spectroscopy it was shown that the heparan sulphate isolated from the brine shrimp Artemia franciscana exhibits structural ...