Browsing by Subject "stem cells"
Now showing items 1-10 of 17
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Aberrant signaling pathways in medulloblastomas: a stem cell connection
(Academia Brasileira de Neurologia - ABNEURO, 2010-12-01)Medulloblastoma is a highly malignant primary tumor of the central nervous system. It represents the most frequent type of solid tumor and the leading cause of death related to cancer in early childhood. Current treatment ...
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Biomateriais na reparação do sistema nervoso central: uso de nanofibras sintéticas biodegradáveis como suporte para transplante celular e nanopartículas contendo cxcl12 no recrutamento de células-tronco endógenas
(Universidade Federal de São Paulo (UNIFESP), 2016-12-31)Central nervous system (CNS) disorders are highly debilitating and with few therapeutic options. Stem cells are a therapeutic promise for these diseases. The two main strategies described in literature are exogenous stem ...
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BONE MARROW STEM CELLS in FACIAL NERVE REGENERATION FROM ISOLATED STUMPS
(Wiley-Blackwell, 2013-09-01)IntroductionSevere lesions in the facial nerve may have extensive axonal loss and leave isolated stumps that impose technical difficulties for nerve grafting. Methods: We evaluated bone marrow stem cells (BMSC) in a silicone ...
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Células-tronco mesenquimais: células ideais para a regeneração cardíaca?
(Sociedade Brasileira de Hemodinâmica e Cardiologia Intervencionista - SBHCI, 2010-01-01)Mesenchymal stem cells represent a rare subpopulation of bone marrow stem cells (< 0.01% of mononuclear cells originated from bone marrow) with capacity for in vitro mitotic expansion. Because they split and proliferate ...
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Desenvolvimento de um método não enzimático de isolamento e produção em alta escala de células-tronco de cordão umbilical e polpa dentária com amplo potencial terapêutico
(Universidade Federal de São Paulo (UNIFESP), 2014-05-28)Introduction: Cell-based products are becoming increasingly important as potential biotherapies. It is expected that cell therapy will cause a huge impact on the health sector in the coming decades. However, large-scale ...
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Ectopic development of skeletal muscle induced by subcutaneous transplant of rat satellite cells
(Assoc Bras Divulg Cientifica, 2005-03-01)The present study analyzes the ectopic development of the rat skeletal muscle originated from transplanted satellite cells. Satellite cells (106 cells) obtained from hindlimb muscles of newborn female 2BAW Wistar rats were ...
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Enxerto das células-tronco imaturas da polpa dentária humana para tratamento da deficiência de células-tronco límbicas
(Universidade Federal de São Paulo (UNIFESP), 2015-11-26)The limbal stem cells are responsible for maintaining the integrity of the corneal epithelium. In his absence the peripheral conjunctival epithelium invades the surface of the cornea, resulting in opacification and severe ...
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Expressão de marcadores relacionados ao potencial de diferenciação celular da articulação temporomandibular (atm) em fetos humanos
(Universidade Federal de São Paulo (UNIFESP), 2016-05-31)This study evaluated the immunohistochemical expression of proteins: OCT-4, NANOG, SOX-2, SOX-5 and STAT-3, which together characterize pluripotent embryonic cells. Methods: Twenty ATMs human fetuses aged between 12 and ...
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In vivo and in vitro effect of killed Propionibacterium acnes and its purified soluble polysaccharide on mouse bone marrow stem cells and dendritic cell differentiation
(Elsevier B.V., 2006-01-01)Among the effects exerted by Propionibacterium acnes, a most relevant one is its capacity to modulate the Th1/Th2 cellular immune response. This effect depends on the induction and activation of antigen presenting cells, ...
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Indicações de transplante de células-tronco hematopoéticas em pediatria: consenso apresentado no I Encontro de Diretrizes Brasileiras em Transplante de Células-Tronco Hematopoéticas - Sociedade Brasileira de Transplante de Medula Óssea, Rio de Janeiro, 2009
(Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2010-01-01)The Brazilian Bone Marrow Transplant Society (SBTMO) held its First Meeting on Bone Marrow Transplant Guidelines in 2009. A working group of hematologists and oncologists with experience in pediatrics was formed to review ...