Now showing items 1-10 of 49

    • Adaptação cultural, validade e confiabilidade da versão brasileira do Inventário de Habilidades de Vida Independente: versão do paciente (ILSS-BR/P), na esquizofrenia 

      Martini, Larissa Campagna [UNIFESP]; Attux, Cecília [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Mari, Jair de Jesus [UNIFESP] (Faculdade de Medicina da Universidade de São Paulo, 2012-01-01)
      BACKGROUND: There is a strong association between good psychosocial functioning and the ability to carry out everyday tasks in patients with schizophrenia. Valid instruments become increasingly necessary to evaluate the ...

    • AKT1 and neurocognition in schizophrenia 

      Pinheiro, Andrea Poyastro [UNIFESP]; Keefe, Richard S. E.; Skelly, Tara; Olarte, Megan; Leviel, Keren; Lange, Leslie A.; Lange, Ethan M.; Stroup, T. Scott; Lieberman, Jeffrey; Sullivan, Patrick F. (Informa Healthcare-taylor & Francis, 2007-02-01)
      Objective: Previous research has shown conflicting results for the significance of five v-akt murine thymoma viral oncogene homolog 1 (AKT1) single-nucleotide polymorphisms (SNPs) to the aetiology of schizophrenia. ...

    • Analytical approaches for lipidomics and its potential applications in neuropsychiatric disorders 

      Sethi, Sumit [UNIFESP]; Hayashi, Mirian A. [UNIFESP]; Sussulini, Alessandra; Tasic, Ljubica; Brietzke, Elisa [UNIFESP] (Taylor & Francis Ltd, 2017)
      Objectives: In this review, the authors discuss an overview of lipidomics followed by in-depth discussion of its application to the study of human diseases, including extraction methods of lipids, analytical techniques and ...

    • Ateliê de desenho e Rorschach: estudo fenômeno-estrutural 

      Santoantonio, Jacqueline [UNIFESP]; Antúnez, Andrés Eduardo Aguirre (Universidade de São Paulo, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, 2010-04-01)
      The production of drawings in group and the Rorschach test were used in the course of a semi-intensive psychiatric treatment of a patient with schizophrenia cared for in a Psychosocial Care Center. The structural-phenomenological ...

    • Biomarcadores periféricos nos transtornos psicóticos: a influência de características clínicas, estágio da doença e tratamento 

      Noto, Cristiano de Souza [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-10-16)
      INTRODUCTION: Schizophrenia is a chronic disease, with considerable impact on live of individuals and their families. Its origin is related to a complex interaction between genetic and environmental factors during brain ...

    • Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats 

      Peres, Fernanda Fiel [UNIFESP]; Leyin, Raquel [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Gouvea, Douglas Albuquerque [UNIFESP]; Almeida, Valeria [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Lungato, Lisandro [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E. C.; Crippa, Jose A.; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena da [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Media Sa, 2016)
      Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's disease patients, CBD is able to attenuate ...

    • Cannabidiol, among Other Cannabinoid Drugs, Modulates Prepulse Inhibition of Startle in the SHR Animal Model: Implications for Schizophrenia Pharmacotherapy 

      Peres, Fernanda F. [UNIFESP]; Levin, Raquel [UNIFESP]; Almeida, Valeria [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E.; Crippa, Jose A.; Abilio, Vanessa C. [UNIFESP] (Frontiers Media Sa, 2016)
      Schizophrenia is a severe psychiatric disorder that involves positive, negative and cognitive symptoms. Prepulse inhibition of startle reflex (PPI) is a paradigm that assesses the sensorimotor gating functioning and is ...

    • Caracterização do papel das endopeptidases (ndel1 e da eca) na esquizofrenia: um estudo translacional e multimodal 

      Araripe Neto, Ary Gadelha de Alencar [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-04-30)
      Background: NDEL1 oligopeptidase interacts with schizophrenia (SCZ) risk gene product DISC1 and mediates several functions related to neurite outgrowth and neuronal migration. NDEL1 also hydrolyses neuropeptides previously ...

    • Changes in gene expression and methylation in the blood of patients with first-episode psychosis 

      Ota, Vanessa Kiyomi [UNIFESP]; Noto, Cristiano [UNIFESP]; Gadelha, Ary [UNIFESP]; Santoro, Marcos Leite [UNIFESP]; Spindola, Leticia Maria [UNIFESP]; Gouvea, Eduardo Sauerbronn [UNIFESP]; Stilhano, Roberta Sessa [UNIFESP]; Ortiz, Bruno Bertolucci [UNIFESP]; Silva, Patricia Natalia [UNIFESP]; Sato, Joao Ricardo [UNIFESP]; Han, Sang Won [UNIFESP]; Cordeiro, Quirino [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Belangero, Sintia Iole [UNIFESP] (Elsevier B.V., 2014-11-01)
      Schizophrenia is a severe mental health disorder with high heritability. the investigation of individuals during their first-episode psychosis (FEP), before the progression of psychotic disorders and especially before ...

    • Chromosome X Aneuploidy in Brazilian Schizophrenic Patients 

      De Moraes, Leopoldo Silva; Khayat, Andre Salim [UNIFESP]; Lima De Lima, Patricia Danielle; Lima, Eleonidas Moura; Pinto, Giovanny Reboucas; Leal, Mariana Ferreira [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP]; Burbano, Rommel Rodriguez [UNIFESP] (Int Inst Anticancer Research, 2010-05-01)
      The identification of cytogenetic abnormalities in schizophrenic patients may provide clues to the genes involved in this disease. For this reason, a chromosomal analysis of samples from 62 schizophrenics and 70 controls ...