Browsing by Subject "risk factor"
Now showing items 1-10 of 15
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Apolipoprotein A-V gene polymorphism -1131T > C and Alzheimer's disease
(Ios Press, 2006-12-01)Alzheimer's disease (AD) is the most common neurodegenerative disorder in the elderly and is also considered a progeroid genetic syndrome. The etiology of AD is complex and the mechanisms underlying its pathophysiology ...
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Association of increased levels of homocysteine and peripheral arterial disease in a Japanese-Brazilian population
(W B Saunders Co Ltd, 2007-07-01)Objectives. Our aim was to evaluate the possible association between homocysteine levels and peripheral arterial disease (PAD) in a population-based study of Japanese-Brazilians.Materials and methods. This cross-sectional ...
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Epidemiology of bacteremia and factors associated with multi-drug-resistant gram-negative bacteremia in hematopoietic stem cell transplant recipients
(Nature Publishing Group, 2007-06-01)The incidence of Gram-negative bacteremia has increased in hematopoietic stem cell transplant (HSCT) recipients. We prospectively collected data from 13 Brazilian HSCT centers to characterize the epidemiology of bacteremia ...
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Factor VArg(306)-> Thr (factor V Cambridge) and factor V Arg(306)-> Gly mutations in venous thrombotic disease
(Blackwell Science Ltd, 1998-12-01)We investigated the prevalence of two reported mutations of the factor V gene (factor V Arg(306) --> Thr, or factor V Cambridge, and factor V Arg(306) --> Gly) in 104 relatively young patients with verified venous thrombosis ...
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Fibrinogênio como fator de risco independente de doença vascular cerebral
(Academia Brasileira de Neurologia - ABNEURO, 1997-01-01)We have studied fibrinogen levels (Clauss technique) in atherothrombotic ischemic stroke patients, in order to determine its role as a thombogenic risk factor. Twenty nine patients (20 men and 9 women) between 25 and 79 ...
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High prevalence of hepatitis C infection in a Brazilian prison: identification of risk factors for infection
(Brazilian Society of Infectious Diseases, 2001-06-01)Hepatitis C virus (HCV) causes infectious hepatitis worldwide. It is transmitted mainly by blood products and sharing of intravenous paraphernalia during illicit drug use. High prevalence rates have been described among ...
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Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients
(Lippincott Williams & Wilkins, 2002-04-01)Fasting total homocysteine (tHcy) and the methylenetetrahydrofolate reductase (MTHFR) C677T mutation were evaluated in 91 patients with venous thromboembolism and without acquired thrombophilia, and in 91 age-matched and ...
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Identification of polymorphisms in the 5 '-untranslated region of the TAFI gene: relationship with plasma TAFI levels and risk of venous thrombosis
(Ferrata Storti Foundation, 2001-05-01)Background and Objectives. Thrombin activatable fibrinolysis inhibitor (TAFI) plays an important role in hemostasis, functioning as a potent fibrinolysis inhibitor. TAFI gene variations may contribute to plasma TAFI levels ...
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Interleukin-6 polymorphisms and the risk of cervical cancer
(Blackwell Publishing, 2006-05-01)Recent data implicate that cytokine gene polymorphisms are important in pathogenesis of various neoplastic and nonneoplastic human diseases, and it was recently suggested that polymorphisms in interleukin (IL)-6 might ...
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Interleukin-8 gene polymorphism -251T > A and Alzheimer's disease
(Ios Press, 2007-01-01)