Now showing items 1-10 of 15

    • Antidyskinetic effects of risperidone on animal models of tardive dyskinesia in mice 

      Carvalho, R. C.; Silva, R. H.; Abilio, V. C.; Barbosa, P. N.; Frussa, R. (Elsevier B.V., 2003-04-15)
      The effects of risperidone, an atypical neuroleptic, were investigated on two animal models of tardive dyskinesia (TD). the repeated administration of reserpine (1.0 mg/kg) or haloperidol (2.0 mg/kg) induces orofacial ...

    • Behavioral effects of MK-801 on reserpine-treated mice 

      Dutra, R. C.; Andreazza, A. P.; Andreatini, R.; Tufik, Sergio [UNIFESP]; Vital, Maria ABF [UNIFESP] (Elsevier B.V., 2002-04-01)
      The effects of dizocilpine (MK-801), a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, were studied on dopamine-related behaviors induced by reserpine treatments. This study focuses on behavioral syndromes ...

    • Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats 

      Peres, Fernanda Fiel [UNIFESP]; Leyin, Raquel [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Gouvea, Douglas Albuquerque [UNIFESP]; Almeida, Valeria [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Lungato, Lisandro [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E. C.; Crippa, Jose A.; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena da [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Media Sa, 2016)
      Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's disease patients, CBD is able to attenuate ...

    • Concomitant development of oral dyskinesia and memory deficits in reserpine-treated male and female mice 

      Silva, R. H.; Abilio, V. C.; Torres-Leite, D.; Bergamo, M.; Chinen, C. C.; Claro, F. T.; Carvalho, R. D.; Frussa, R. (Elsevier B.V., 2002-05-14)
      It has been suggested that reserpine-induced oral dyskinesia in rats may provide a new animal model of tardive dyskinesia. Both cognitive deficits and gender have been associated with the development of tardive dyskinesia. ...

    • Effects of age on a new animal model of tardive dyskinesia 

      Bergamo, M.; Abilio, V. C.; Queiroz, CMT; Barbosa, H. N.; Abdanur, LRA; Frussa, R. (Elsevier B.V., 1997-11-01)
      The effects of age were studied on a new animal model of tardive dyskinesia, i.e., the quantification of oral dyskinesia in rats repeatedly treated with reserpine. Adult and old rats received two injections of reserpine ...

    • Effects of baclofen on reserpine-induced vacuous chewing movements in mice 

      Castro, JPMV; Frussa-Filho, R.; Fukushiro, D. F.; Silva, R. H.; Medrano, W. A.; Ribeiro, R. D.; Abilio, V. C. (Elsevier B.V., 2006-02-15)
      We have described that GABA mimetic drugs present the ability to inhibit the expression of reserpine-induced oral movements. in this respect, oral movements is associated with important neuropathologies. This study ...

    • Effects of buspirone on an animal model of tardive dyskinesia 

      Queiroz, Claudio MT [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 1999-11-01)
      1. the effects of buspirone were studied on an animal model of tardive dyskinesia, i.e., the quantification of orofacial dyskinesia in rats repeatedly treated with reserpine.2. Rats were co-treated with saline [SAL] or ...

    • Effects of gabaergic drugs on reserpine-induced oral dyskinesia 

      Peixoto, M. R.; Araujo, N. P.; Silva, R. H.; Castro, JPMV; Fukushiro, D. F.; Faria, R. R.; Zanier-Gomes, P. H.; Medrano, W. A.; Frussa-Filho, R.; Abilio, V. C. (Elsevier B.V., 2005-05-07)
      Recently we have described the antidyskinetic property of the GABA mimetic drugs valproic acid and topiramate on reserpine-induced oral dyskinesia. in this respect, oral dyskinesia has been associated with important ...

    • Effects of monosialoganglioside on a new model of tardive dyskinesia 

      Vital, MABF; Frussa-Filho, Roberto [UNIFESP]; Palermo Neto, J. (Elsevier B.V., 1997-10-01)
      1- the effects of monosialoganglioside GM(1) were studied on a new model of tardive dyskinesia, i.e., the frequency of spontaneous tongue protrusions in rats repeatedly treated with reserpine.2- Rats were co-treated with ...

    • Effects of valproic acid on an animal model of tardive dyskinesia 

      Peixoto, M. F.; Abilio, V. C.; Silva, R. H.; Frussa, R. (Elsevier B.V., 2003-06-16)
      GABAergic hypofunction in the basal ganglia is stated as an important mechanism underlying the pathophysiology of tardive dyskinesia. the present study investigates the effects of the GABA-mimetic drug valproic acid (VA) ...