Now showing items 1-10 of 83

    • Age-dependent consequences of seizures and the development of temporal lobe epilepsy in the rat 

      Dube, C.; Fernandes, MJDS; Nehlig, A. (Karger, 2001-05-01)
      The age-related functional changes underlying epileptogenesis remain to be clarified. in the present study, we explored the correlation between metabolic changes, neuronal damage and epileptogenesis during the acute, silent ...

    • Apoptosis and testicular alterations in albino rats treated with etoposide during the prepubertal phase 

      Stumpp, Taiza [UNIFESP]; Sasso-Cerri, Estela [UNIFESP]; Freymüller-Haapalainen, Edna [UNIFESP]; Miraglia, Sandra Maria [UNIFESP] (Wiley-Blackwell, 2004-07-01)
      Etoposide is a podophyllotoxin semiderivative that is used in a variety of chemotherapy treatments, including therapy for children tumors. This drug promotes the formation of a ternary DNA-topoisomerase II-etoposide complex ...

    • An approximate estimate of the ion-activity product of calcium oxalate in rat urine 

      Tiselius, H. G.; Ferraz, RRN; Heilberg, I. P. (Springer, 2003-12-01)
      The objective of this report was to derive a simplified approximate estimate of the ion-activity product of calcium oxalate (AP(CaOx)) in rat urine. the relative effect of each urine variable was assessed by means of ...

    • Aspectos histológicos de fragmentos esplênicos autotransplantados em ratos 

      Freitas, Silvio Henrique; Dória, Renata Gebara Sampaio; Mendonça, Fábio de Souza; Evêncio Neto, J.; Simões, Manuel de Jesus [UNIFESP]; Camargo, Lázaro Manoel (Universidade Federal de Minas Gerais, Escola de Veterinária, 2010-06-01)
      The splenic tissue autograft viability (one third of the spleen) associated to parcial splenectomy was studied to verify the evolutive kinetic of its regeneration by macroscopic and histological aspects. Twenty-eight adult ...

    • Aspectos morfológicos, morfométricos e ultraestruturais do baço de ratos após o clampeamento total do pedículo hepático 

      Freitas, Silvio Henrique; Evêncio Neto, Joaquim; Dória, Renata Gebara Sampaio; Mendonça, Fábio de Souza; Simões, Manuel de Jesus [UNIFESP]; Camargo, Lázaro Manoel; Sebe, A.a. (Universidade Federal de Minas Gerais, Escola de Veterinária, 2009-12-01)
      The macro and microscopic alterations that occurred in the spleen during an ischemia produced by the hepatic pedicle total clamping were studied. Forty male rats were distributed in four groups of 10 animals each. The ...

    • Blockage of dopaminergic D-2 receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation 

      Lima, Marcelo M. S. [UNIFESP]; Andersen, Monica L. [UNIFESP]; Reksidler, Angela B.; Silva, Andressa [UNIFESP]; Zager, Adriano [UNIFESP]; Zanata, Silvio M.; Vital, Maria A. B. E.; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2008-04-09)
      Dopamine (DA) has, as of late, become singled out from the profusion of other neurotransmitters as what could be called a key substance, in the regulation of the sleep-wake states. We have hypothesized that dopaminergic ...

    • Brain Electrical Activity After Acute Hippocampal Stimulation in Awake Rats 

      Silva, Jose C. da [UNIFESP]; Amorim, Henrique [UNIFESP]; Scorza, Fulvio A. [UNIFESP]; Cavalheiro, Esper A. [UNIFESP]; Cukiert, Arthur [UNIFESP] (Wiley-Blackwell, 2013-03-01)
      Objective: We describe the electrocorticographic findings after hippocampal stimulation in normal awake rats. Methods: Six male Wistar rats were implanted bilaterally with neocortical and hippocampal electrodes. the animals ...

    • c-FOS Expression After Hippocampal Deep Brain Stimulation in Normal Rats 

      Silva, Jose C. da [UNIFESP]; Scorza, Fulvio A. [UNIFESP]; Nejm, Mariana B. [UNIFESP]; Cavalheiro, Esper A. [UNIFESP]; Cukiert, Arthur [UNIFESP] (Wiley-Blackwell, 2014-04-01)
      ObjectivesWe studied the effects of Hip-deep brain stimulation (DBS) on the expression of the inducible transcription factor c-FOS in the brain of normal rats.Materials and MethodsTen Wistar rats were anesthetized, and ...

    • Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats 

      Peres, Fernanda Fiel [UNIFESP]; Leyin, Raquel [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Gouvea, Douglas Albuquerque [UNIFESP]; Almeida, Valeria [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Lungato, Lisandro [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E. C.; Crippa, Jose A.; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena da [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Media Sa, 2016)
      Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's disease patients, CBD is able to attenuate ...

    • Cardiorespiratory effects of L-glutamate microinjected into the rat ventral medulla 

      Tolentino-Silva, Fatima Rosaria Paulino [UNIFESP]; Campos, R. R.; Russo, A. K.; Cravo, S. L.; Lopes, O. U. (Elsevier B.V., 1997-04-01)
      We investigated the cardiorespiratory effects elicited by microinjections of L-glutamate (L-glu, 25 nmol, 200 nl) at various sites in the ventral medulla (VMS) of urethane-anesthetized rats. the results demonstrated that ...