Now showing items 1-10 of 41

    • Adipocinas e o diabetes mellitus gestacional 

      Lobo, Thalita Frutuoso [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2013-10-30)
      Introdução: A obesidade é uma condição inflamatória que predispõe ao desenvolvimento do Diabetes Mellitus Gestacional (DMG). Algumas mulheres obesas desenvolvem uma forma mais precoce de DMG, antes do aumento fisiológico ...

    • Analysis of vitamin D receptor gene (VDR) polymorphisms in Turner syndrome patients 

      Bianco, Bianca [UNIFESP]; Verreschi, Ieda T. N. [UNIFESP]; Oliveira, Kelly Cristina de [UNIFESP]; Guedes, Alexis D. [UNIFESP]; Barbosa, Caio P.; Lipay, Monica V. N. [UNIFESP] (Informa Healthcare, 2012-04-01)
      Individuals with Turner syndrome (TS) have increased risk for autoimmune diseases, especially thyroid abnormalities. the function of the vitamin D receptor (VDR) gene is influenced by several genetic polymorphisms which ...

    • Análise do polimorfismo do gene do receptor de melatonina mtnr1b em mulheres com síndrome dos ovários policisticos em uso de metformina e antinconcepcional 

      Iwata, Margareth Chiharu [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-02-12)
      INTRODUCTION.The polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive age in women. The exact pathophysiological mechanism of the syndrome remains unclear, but it is believed that insulin ...

    • APO A-V-1131T -> C polymorphism frequency and its association with morbidity in a Brazilian elderly population 

      Chen, E. S.; Cendoroglo, M. S.; Ramos, L. R.; Araujo, LMQ; Carvalheira, GMG; Labio, R. W. de; Burbano, R. R.; Payao, SLM; Smith, MDC (Walter de Gruyter & Co, 2006-01-01)
      Identification of genetic polymorphisms as risk factors for complex diseases affecting older people can be relevant for their prevention, diagnosis and management. the -1131T -> C polymorphism of the apolipoprotein A-V ...

    • Associação entre polimorfismo SLC6A3 3 UTR VNTR e a resposta ao tratamento da dependência de nicotina 

      Focchi, Gustavo Rubino de Azevedo [UNIFESP]; Silva, Ismael Dale Cotrim Guerreiro da [UNIFESP]; Scivoletto, Sandra (Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro, 2011-01-01)
      Objective: To evaluate the association between response to treatment of nicotine dependence with bupropion and the presence of the polymorphism SLC6A3 3 UTR VNTR, in the gene that codifies the dopaminergic transporter. ...

    • Association analysis of GRK3 gene promoter variants in cocaine abuse 

      Guindalini, Camila; Collier, David; Laranjeira, Ronaldo; Barrett, Tom B.; Kelsoe, John; Castelo, Adauto; Vallada, Homero; Breen, Gerome (Lippincott Williams & Wilkins, 2007-08-01)
      The G protein-coupled receptor kinase 3 gene (GRK3) is a candidate gene for cocaine adiction because it is involved in the regulation of several neurotransmitter receptors, including the response to dopaminergic agonists ...

    • Association between the C3435T single-nucleotide polymorphism of multidrug resistance 1 gene and risk of gastric cancer 

      Oliveira, Juliana [UNIFESP]; Felipe, Aledson Vitor [UNIFESP]; Chang, Paula Y. J. [UNIFESP]; Pimenta, Celia Aparecida Marques [UNIFESP]; Silva, Tiago D. [UNIFESP]; Massud, Joao [UNIFESP]; Forones, Nora Manoukian [UNIFESP] (Spandidos Publ Ltd, 2012-08-01)
      The multidrug resistance 1 (MDR1) gene encodes P-glycoprotein, which confers resistance to antineoplastic drugs, but also affects the kinetic disposition of certain drugs and carcinogens. the C3435T polymorphism of the ...

    • Association of the apolipoprotein A-IV : 360 Gln/His polymorphism with cerebrovascular disease, obesity, and depression in a Brazilian elderly population 

      Ejchel, Tatiana Flank [UNIFESP]; Araujo, LMQ; Ramos, L. R.; Cendoroglo, M. S.; Smith, MDC (Wiley-Blackwell, 2005-05-05)
      The identification of genetic polymorphisms as risk factors for complex diseases can be relevant for their prevention, diagnosis, and prognosis. the apolipoprotein A-IV: 360 Gln/His polymorphism was investigated in 383 ...

    • Association of the CYP17 gene polymorphism with risk for uterine leiomyoma in Brazilian women 

      Vieira, Lucinda Coelho Esperança [UNIFESP]; Gomes, Mariano Tamura Vieira [UNIFESP]; Castro, Rodrigo de Aquino [UNIFESP]; Nogueira-de-Souza, Naiara Corrêa [UNIFESP]; Silva, Ismael Dale Cotrim Guerreiro da [UNIFESP]; Baracat, Edmund Chada [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP] (Informa Healthcare, 2008-01-01)
      Background. Uterine leiomyoma is the most common pelvic tumor in women of reproductive age. It is well established that endogenous sex hormones are involved in disease pathogenesis, and polymorphisms in genes encoding ...

    • Association of the PPP3CA c.249G>A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients 

      Salgado, Patricia C.; Genvigir, Fabiana D. V.; Felipe, Claudia Rosso [UNIFESP]; Tedesco-Silva Junior, Hélio [UNIFESP]; Pestana, Jose Osmar Medina [UNIFESP]; Doi, Sonia Q.; Hirata, Mario H.; Hirata, Rosario D. C. (Dove Medical Press Ltd, 2017)
      Background: The effects of genetic variants related to the pharmacodynamic mechanisms of immunosuppressive drugs on their therapeutic efficacy and safety have been poorly explored. This study was performed to investigate ...