Browsing by Subject "pilocarpine"
Now showing items 1-10 of 66
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Acute or chronic effects of cannabinoids on spontaneous or pharmacologically induced yawning in rats
(Elsevier B.V., 2002-12-01)Yawning is a reflex or event that is not fully understood. It is controlled by many neurotransmitters and neuropeptides and can be induced pharmacologically by cholinergic or dopaminergic agonists. Amongst their many ...
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Altered anxiety-related and abnormal social behaviors in rats exposed to early life seizures
(Frontiers Research Foundation, 2013-05-09)Neonatal seizures are the most common manifestation of neurological dysfunction in the neonate. the prognosis of neonatal seizures is highly variable, and the controversy remains whether the severity, duration, or frequency ...
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Aplicação do método de interferência de rna na caracterização do papel do receptor p2x7 na epilepsia do lobo temporal
(Universidade Federal de São Paulo (UNIFESP), 2014-12-30)Introduction: Epilepsy is a serious neurological disease, and temporal lobe epilepsy (TLE) is the most common type in adults. Hippocampal sclerosis is the major histopathological alteration in ELT. Hippocampal sclerosis ...
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Avaliação de parâmetros cardíacos em animais com epilepsia: possível causa de morte súbita?
(Academia Brasileira de Neurologia - ABNEURO, 2005-12-01)Among the causes for sudden death in epilepsy, cardiac dysfunction has been an area of interest. Based on this, the aim of our study was to evaluate the heart rate (in vivo and in vitro) and ventricular pressure in vitro ...
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Avaliação do tratamento com n-acetilcisteína nas manifestações comportamentais e histológicas causadas pela pilocarpina
(Universidade Federal de São Paulo (UNIFESP), 2015-06-30)Epilepsy is the most common neurological dysfunction, affecting more than 65 million people worldwide. Temporal lobe epilepsy (TLE) is the most prevalent form in adults, affecting 40% of all cases. Hippocampal sclerosis ...
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BASAL DENDRITES ARE PRESENT in NEWLY BORN DENTATE GRANULE CELLS of YOUNG BUT NOT AGED PILOCARPINE-TREATED CHRONIC EPILEPTIC RATS
(Elsevier B.V., 2010-10-27)Epilepsy is known to influence hippocampal dentate granule cell (DGC) layer neurogenesis. in young adult rats, status epilepticus (SE) increases the number DGC newly borne cells and basal dendrites (BD), which persist at ...
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Blockade of pilocarpine- or kainate-induced mossy fiber sprouting by cycloheximide does not prevent subsequent epileptogenesis in rats
(Elsevier B.V., 1997-05-02)Post-injury sprouting of hippocampal messy fibers has been suggested to be a causal mechanism underlying the development of temporal lobe epilepsy. However, this hypothesis rests entirely on indirect correlational evidence. ...
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Caracterização fisiopatológica do sistema renina-angiotensina durante o status epilepticus induzido pela pilocarpina em camundongos transgênicos que expressam tonina de rato
(Universidade Federal de São Paulo (UNIFESP), 2013-12-20)Objectives: To evaluate the influence of pilocarpine induced long-term convulsive seizure in transgenic mice with overexpressed plasma and brain Ang II. Methods: Using a 320mg/kg pilocarpine dose to induce SE. Following ...
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Castration in female rats modifies the development of the pilocarpine model of epilepsy
(Elsevier B.V., 2002-05-01)Previous studies have shown that the susceptibility to pilocarpine-induced status epilepticus (SE) in female rats changes according to estrous cycle phases. These studies have also shown that following pilocarpine ...
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Cholinergic modulation of inhibitory avoidance impairment induced by paradoxical sleep deprivation
(Elsevier B.V., 2000-05-01)1. Male Wister rats were submitted to paradoxical sleep deprivation for 96 hr by a modified multiple platform technique.2. Training of step-through inhibitory avoidance was performed immediately after the last day of ...
