Now showing items 1-10 of 22

    • Acoustic arousal responses in children with obstructive sleep apnea 

      Moreira, G. A.; Tufik, Sergio [UNIFESP]; Nery, L. E.; Lutz, J.; Verfaille, K.; Luan, X. Q.; Marcus, C. L. (Wiley-Blackwell, 2005-10-01)
      Our objectives were to study the arousal responses to nonrespiratory (acoustic) stimuli in children with obstructive sleep apnea syndrome (OSAS). the acoustic arousal response was studied in children with OSAS due to ...

    • Acute effect of nasal continuous positive air pressure on the ventilatory control of patients with obstructive sleep apnea 

      Moura, SMT; Bittencourt, L. R.; Bagnato, Maurício da Cunha [UNIFESP]; Lucas, SR; Tufik, Sergio [UNIFESP]; Nery, L. E. (Karger, 2001-05-01)
      Background: Sleep fragmentation can decrease the awake ventilatory control. Since patients with obstructive sleep apnea (OSA) patients exhibit sleep fragmentation linked to respiratory events, their ventilatory control ...

    • Andersen syndrome: an association of periodic paralysis, cardiac arrhythmia and dysmorphic abnormalities 

      Tengan, Célia Harumi [UNIFESP]; Antunes, Antonio C. [UNIFESP]; Bauab, José R. [UNIFESP]; Prado, Gilmar Fernandes do [UNIFESP]; Manzano, Gilberto Mastrocola [UNIFESP]; Gabbai, Alberto Alain [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2006-09-01)
      Andersen syndrome (AS) is a rare disease characterized by the presence of periodic paralysis (PP), cardiac arrhythmia and dysmorphic abnormalities. We report herein the first Brazilian patient presenting AS who also had ...

    • Clinical, anthropometric and upper airway anatomic characteristics of obese patients with obstructive sleep apnea syndrome 

      Hora, Francisco; Napolis, Lara Maris; Daltro, Carla; Kodaira, Sergio Keidi; Tufik, Sergio [UNIFESP]; Togeiro, Sonia Maria; Nery, Luiz Eduardo (Karger, 2007-01-01)
      Background: Obese subjects are at increased risk of developing obstructive sleep apnea syndrome (OSAS). However, the individual role of local (i.e., upper airway-related) and general (clinical and whole-body anthropometric) ...

    • Commentary: Stress Signal Network between Hypoxia and ER Stress in Chronic Kidney Disease 

      Tempaku, Priscila F. [UNIFESP]; Tufik, Sergio [UNIFESP]; Hirotsu, Camila [UNIFESP] (Frontiers Media Sa, 2017)
    • Comparison of AutoSet (TM) and polysomnography for the detection of apnea-hypopnea events 

      Bagnato, Maurício da Cunha [UNIFESP]; Nery, Luiz Eduardo [UNIFESP]; Togeiro, Sonia Maria [UNIFESP]; Bittencourt, Lia Rita Azeredo [UNIFESP]; Tufik, Sergio [UNIFESP] (Associação Brasileira de Divulgação Científica, 2000-05-01)
      The use of the flow vs time relationship obtained with the nasal prongs of the AutoSetä (AS) system (diagnosis mode) has been proposed to detect apneas and hypopneas in patients with reasonable nasal patency. Our aim was ...

    • Does Obstructive Sleep Apnea Impair the Cardiopulmonary Response to Exercise? 

      Rizzi, Camila Furtado [UNIFESP]; Cintra, Fatima [UNIFESP]; Mello-Fujita, Luciane [UNIFESP]; Rios, Lais França [UNIFESP]; Mendonça, Elisangela Trevisan de [UNIFESP]; Feres, Marcia Cristina [UNIFESP]; Tufik, Sergio [UNIFESP]; Poyares, Dalva [UNIFESP] (Amer Acad Sleep Medicine, 2013-04-01)
      Study Objectives: the aim of this study was to evaluate cardiopulmonary exercise performance in lean and obese patients with obstructive sleep apnea (OSA) compared with controls.Design: Case-control study.Setting: the study ...

    • Efeito das diferentes regras de marcação de eventos respiratórios na classificação da apneia obstrutiva do sono 

      Garbuio, Silvério Aparecido [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-06-30)
      Introduction: Despite the high relevance of the Apnea and Hypopnea Index (AHI) and the Respiratory Disturbance Index (RDI) in the diagnosis of Obstructive Sleep Apnea (OSA), there is still a high disagreement in the ...

    • Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults 

      Taranto-Montemurro, Luigi; Sands, Scott A.; Azarbarzin, Ali; Marques, Melania; de Melo, Camila M. [UNIFESP]; Edwards, Bradley A.; Eckert, Danny J.; Messineo, Ludovico; White, David P.; Wellman, Andrew (Amer Thoracic Soc, 2017)
      Rationale: The reduction in upper airway muscle activity from wakefulness to sleep plays a key role in the development of obstructive sleep apnea. Potassium (K+) channels have been recently identified as the downstream ...

    • The Effect of Donepezil on Arousal Threshold and Apnea-Hypopnea Index A Randomized, Double-Blind, Cross-Over Study 

      Li, Yanru; Owens, Robert L.; Sands, Scott; Orr, Jeremy; Moraes, Walter [UNIFESP]; DeYoung, Pamela; Smales, Erik; Jen, Rachel; Malhotra, Atul (Amer Thoracic Soc, 2016)
      Rationale: Obstructive sleep apnea (OSA) has multiple pathophysiological causes. A low respiratory arousal threshold (ArTh) and a high loop gain (unstable ventilatory control) can contribute to recurrent respiratory events ...