Browsing by Subject "neuroplasticity"
Now showing items 1-6 of 6
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Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy
(Elsevier B.V., 2005-12-20)Cycloheximide influences synaptic reorganization resulting from pilocarpine-induced status epilepticus (SE). To investigate the possible behavioral consequences of this effect, we subjected animals to pilocarpine-induced ...
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BENEFICIAL INFLUENCE of PHYSICAL EXERCISE FOLLOWING STATUS EPILEPTICUS in the IMMATURE BRAIN of RATS
(Elsevier B.V., 2014-08-22)Studies in adult animals have demonstrated a beneficial effect of physical exercise on epileptic insults. Although the effects of physical exercise on the mature nervous system are well documented, its influence on the ...
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Cytokines in schizophrenia: Possible role of anti-inflammatory medications in clinical and preclinical stages
(Wiley-Blackwell, 2012-06-01)Aims: in this paper, we review the literature on the efficacy of anti-inflammatory agents as neuroprotectors in clinical and preclinical stages of schizophrenia. Method: A synthetic and integrative approach was applied to ...
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Investigação do exercício de força agudo e cronico na expressão de fatores neurotróficos e proteínas sinápticas na formação hipocampal de ratos
(Universidade Federal de São Paulo (UNIFESP), 2015-02-26)Introduction: The scientific literature has demonstrated the role of strength exercise in health and brain function in humans. Despite recent studies have demonstrated improvement in cognition and quality of life in humans ...
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Metformin: Repurposing Opportunities for Cognitive and Mood Dysfunction
(Bentham Science Publ Ltd, 2014-01-01)Background: Cognitive deficits differentially affect individuals with type 2 diabetes mellitus (T2DM) and mood disorders. Accumulating evidence implicates disturbances in metabolism as salient to cognitive function. Thus, ...
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N-acetylcysteine as a potentially useful medication to prevent conversion to schizophrenia in at-risk individuals
(Walter de Gruyter & Co, 2012-08-01)Schizophrenia is a chronic and often severe psychotic disorder. Its causes include imbalances in mediators involved in neuroplasticity, apoptosis, cell resilience and dendritic arborization. Among these mediators, oxidative ...