Browsing by Subject "nerve regeneration"

Now showing items 1-10 of 11

    • Bone marrow cells are able to increase vessels number during repair of sciatic nerve lesion 

      Fernandes, Marcela [UNIFESP]; Valente, Sandra Gomes [UNIFESP]; Silva Fernandes, Maria Jose da [UNIFESP]; Villar Felix, Evandro Penteado [UNIFESP]; Naffah Mazzacoratti, Maria da Graca [UNIFESP]; Scerni, Debora Amado [UNIFESP]; Gomes dos Santos, Joao Baptista [UNIFESP]; Leite, Vilnei Mattioli [UNIFESP]; Faloppa, Flavio [UNIFESP] (Elsevier B.V., 2008-05-15)
      The aim of this study was to compare the outcomes of nerve autografts (GRF) and venous grafts containing mononuclear bone marrow cells (BMCs) in sciatic nerve-lesioned rats. Control animals underwent sham operations (SHAM), ...

    • BONE MARROW STEM CELLS in FACIAL NERVE REGENERATION FROM ISOLATED STUMPS 

      Salomone, Raquel; Bento, Ricardo F.; Costa, Heloisa J. Z. R.; Azzi-Nogueira, Deborah; Ovando, Patricia C. [UNIFESP]; Da-Silva, Cira F.; Zanatta, Daniela B.; Strauss, Bryan E.; Haddad, Luciana A. (Wiley-Blackwell, 2013-09-01)
      IntroductionSevere lesions in the facial nerve may have extensive axonal loss and leave isolated stumps that impose technical difficulties for nerve grafting. Methods: We evaluated bone marrow stem cells (BMSC) in a silicone ...

    • Bone marrow-derived mesenchymal stem cells versus adipose-derived mesenchymal stem cells for peripheral nerve regeneration 

      Fernandes, Marcela [UNIFESP]; Valente, Sandra Gomes [UNIFESP]; Sabongi, Rodrigo Guerra [UNIFESP]; Gomes dos Santos, Joao Baptista [UNIFESP]; Leite, Vilnei Mattioli [UNIFESP]; Ulrich, Henning; Nery, Arthur Andrade; da Silva Fernandes, Maria Jose [UNIFESP] (Medknow Publications & Media Pvt Ltd, 2018)
      Studies have confirmed that bone marrow-derived mesenchymal stem cells (MSCs) can be used for treatment of several nervous system diseases. However, isolation of bone marrow-derived MSCs (BMSCs) is an invasive and painful ...

    • CD11b+GR1+Myeloid Cells Secrete NGF and Promote Trigeminal Ganglion Neurite Growth: Implications for Corneal Nerve Regeneration 

      Sarkar, Joy; Chaudhary, Shweta; Jassim, Sarmad H.; Ozturk, Okan; Chamon, Wallace [UNIFESP]; Ganesh, Balaji; Tibrewal, Sapna; Gandhi, Sonal; Byun, Yong-Soo; Hallak, Joelle; Mahmud, Dolores L.; Mahmud, Nadim; Rondelli, Damiano; Jain, Sandeep (Assoc Research Vision Ophthalmology Inc, 2013-09-01)
      PURPOSE. We characterized fluorescent bone marrow cells (YFP+ BMCs) in the thy1-YFP mouse and determine if they promote trigeminal ganglion (TG) cell neurite growth.METHODS. Excimer laser annular keratectomy was performed ...

    • DOUBLE GENE THERAPY WITH GRANULOCYTE COLONY-STIMULATING FACTOR and VASCULAR ENDOTHELIAL GROWTH FACTOR ACTS SYNERGISTICALLY TO IMPROVE NERVE REGENERATION and FUNCTIONAL OUTCOME AFTER SCIATIC NERVE INJURY in MICE 

      Lopes, F. R. Pereira; Martin, P. K. M. [UNIFESP]; Frattini, F.; Biancalana, A.; Almeida, F. M.; Tomaz, M. A.; Melo, P. A.; Borojevic, R.; Hans, S. W.; Martinez, A. M. B. (Elsevier B.V., 2013-01-29)
      Peripheral-nerve injuries are a common clinical problem and often result in long-term functional deficits. Reconstruction of peripheral-nerve defects is currently undertaken with nerve autografts. However, there is a limited ...

    • Experimental model of facial paralysis by nerve compression in primates (Callithrix sp.): A new model of facial paralysis in small nonhuman primates 

      Neiva, Felipe Costa [UNIFESP]; Borin, Andrei [UNIFESP]; Cinini, Simone [UNIFESP]; Mello, Luiz Eugenio A. M. [UNIFESP]; Cruz, Oswaldo Laercio M. [UNIFESP]; Testa, Jose Ricardo G. [UNIFESP] (Informa Healthcare, 2012-11-01)
      Conclusion: We conclude that facial nerve injury induced by compression is associated with a reasonable time window (4 weeks) that allows possible neurotrophic effects to be analyzed. Additionally, there are no hints of ...

    • Influência do AMP cíclico na regeneração do nervo facial em ratos 

      Borin, Andrei; Toledo, Ronaldo Nunes; Ho, Paulo Lee; Testa, Jose Ricardo Gurgel [UNIFESP]; Cruz, Oswaldo Laércio Mendonça [UNIFESP]; Fukuda, Yotaka [UNIFESP] (ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2008-10-01)
      Promoting facial nerve regeneration is a significant challenge. AIM: To evaluate the possible neurotrophic influence of cyclic AMP on facial nerve regeneration of Wistar rats. METHOD: The right facial nerve of thirty-two ...

    • Modelo experimental comportamental e histológico da regeneração do nervo facial em ratos 

      Borin, Andrei [UNIFESP]; Toledo, Ronaldo Nunes [UNIFESP]; Faria, Simone Damasceno De [UNIFESP]; Testa, Jose Ricardo Gurgel [UNIFESP]; Cruz, Oswaldo Laércio Mendonça [UNIFESP] (ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2006-12-01)
      To setup an experimental model is the first step to study neural regeneration. AIM: Setting up an experimental model on facial nerve regeneration. MATERIAL AND METHODS Wistar rats with complete sectioning and suturing of ...

    • Nerve Regeneration: Is There an Alternative to Nervous Graft? 

      Sabongi, Rodrigo Guerra [UNIFESP]; Lucas Martins de Rizzo, Luiz Augusto [UNIFESP]; Fernandes, Marcela [UNIFESP]; Valente, Sandra Gomes [UNIFESP]; Gomes dos Santos, Joao Baptista [UNIFESP]; Faloppa, Flavio [UNIFESP]; Leite, Vilnei Mattioli [UNIFESP] (Thieme Medical Publ Inc, 2014-11-01)
      Background in nerve injury with nervous gap, no restitution method was found better than the autograft, however, it has the disadvantage of damaging a normal nerve to be used as a graft. Platelet-rich plasma (PRP) is a ...

    • Peripheral nerve regeneration with conduits: use of vein tubes 

      Sabongi, Rodrigo Guerra [UNIFESP]; Fernandes, Marcela [UNIFESP]; Santos, João Baptista Gomes dos [UNIFESP] (Shenyang Editorial Dept Neural Regeneration Res, 2015-04-01)
      Treatment of peripheral nerve injuries remains a challenge to modern medicine due to the complexity of the neurobiological nerve regenerating process. There is a greater challenge when the transected nerve ends are not ...