Browsing by Subject "monoclonal antibody"
Now showing items 1-10 of 16
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Analysis of glycosylinositol phosphorylceramides expressed by the opportunistic mycopathogen Aspergillus fumigatus
(Amer Soc Biochemistry Molecular Biology Inc, 2007-08-01)Acidic glycosphingolipid components were extracted from the opportunistic mycopathogen Aspergillus fumigatus and identified as inositol phosphorylceramide and glycosylinositol phosphorylceramides (GIPCs). Using nuclear ...
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Anti-bevacizumab idiotype antibody vaccination is effective in inducing vascular endothelial growth factor-binding response, impairing tumor outgrowth
(Wiley, 2016)Tumors require blood supply and, to overcome this restriction, induce angiogenesis. Vascular endothelial growth factor (VEGF) plays an important role in this process, which explains the great number of antiangiogenic ...
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Avaliação do anticorpo monoclonal g12f2 para reação de imuno-histoquímica do melanoma murino b16f10
(Universidade Federal de São Paulo (UNIFESP), 2015-02-25)In 2006, at the Department of Microbiology, Immunology and Parasitology of Federal University of São Paulo - UNIFESP, was developed a new monoclonal antibody (mAb), type IgM, designated G12F2, which recognized a single ...
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A cell surface 230 kDa protein from murine melanoma involved with tumor malignancy
(Elsevier B.V., 2008-04-18)Because melanoma incidence has increased at a dramatic rate, it is relevant to identify novel melanoma antigens for diagnosis and develop monoclonal antibodies recognizing such molecules. Some monoclonal antibodies (mAbs), ...
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Characterization of monoclonal antibody MEST-2 specific to glucosylceramide of fungi and plants
(Oxford Univ Press Inc, 2001-02-01)An IgG2a monoclonal antibody anti-glucosylceramide was established and termed MEST-2. High performance thin layer chromatography immunostaining, and solid-phase radioimmunoassay showed that MEST-2 reacts with glucosylceramide ...
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Dendritic Cell Targeting Effectively Boosts T Cell Responses Elicited by an HIV Multiepitope DNA Vaccine
(Frontiers Media Sa, 2017)Despite several efforts in the last decades, an efficacious HIV-1 vaccine is still not available. Different approaches have been evaluated, such as recombinant proteins, viral vectors, DNA vaccines, and, most recently, ...
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Distribution of Trypanosoma cruzi stage-specific epitopes in cardiac muscle of Calomys callosus, BALB/c mice, and cultured cells infected with different infective forms
(Elsevier B.V., 2007-07-01)To examine whether distinct parasite infective forms or the mammalian host could affect the distribution of Trypanosoma cruzi stage-specific epitopes defined by monoclonal antibodies (Mabs) raised against mammalian-stage ...
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Evaluation of an anti-carcinoembryonic monoclonal antibody suitable for immunoscintigraphy
(Assoc Bras Divulg Cientifica, 1999-08-01)An anti-carcinoembryonic antigen (CEA) monoclonal antibody (mAb 6D1.1) was evaluated in vitro and in vivo to determine its suitability as a tracer for immunoscintigraphy of colorectal carcinomas. Determination of mAb ...
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Immunocytochemical localization of heparin in secretory granules of rat peritoneal mast cells using a monoclonal anti-heparin antibody (ST-1)
(Histochemical Soc Inc, 1997-02-01)We performed immunogold labeling with an ST-1 monoclonal antibody (IgM), specific for intact heparin, to define the subcellular localization of heparin in mast cells. Rat peritoneal mast cells were fixed by a modified ...
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Immunolocalization of Leishmania (Viannia) braziliensis membrane antigens recognized by mAbs SST-2, SST-3, and SST-4
(Cambridge Univ Press, 2003-11-01)The immunolocalization of Leishmania (Viannia) braziliensis stage-specific antigens recognized by mAbs was analysed by transmission electron microscopy. the antigen recognized by mAb SST-2 was present at the surface of ...
