Browsing by Subject "monoclonal antibodies"
Now showing items 1-10 of 14
-
Actin-rich structures formed during the invasion of cultured cells by infective forms of Trypanosoma cruzi
(Urban & Fischer Verlag, 1999-12-01)Previous work has shown that Trypanosoma cruzi extracellular amastigotes as well as metacyclic trypomastigotes infect cultured cells in a highly specific parasite form-cell type interaction. In this work we have investigated ...
-
B and T cell responses elicited by monoclonal anti-idiotypic antibody (Ab2 beta) mimicking gp43 from Paracoccidioides brasiliensis
(Blackwell Publishing Ltd, 2004-07-01)Paracoccidioidomycosis is a systemic mycosis endemic in Latin America, with a high prevalence in Brazil, Argentina, Colombia and Venezuela. the aetiological agent of disease is the thermal dimorphic fungus, Paracoccidioides ...
-
Distribution of epitopes of Trypanosoma cruzi amastigotes during the intracellular life cycle within mammalian cells
(Soc Protozoologists, 1997-07-01)In this study we have examined the distribution of epitopes defined by monoclonal antibodies raised against Trypanosoma cruzi amastigotes during the intracellular life cycle of the parasite. We have raised monoclonal ...
-
Evidence of idiotypic modulation in the immune response to gp43, the major antigenic component of Paracoccidioides brasiliensis in both mice and humans
(Blackwell Science Ltd, 1998-10-01)Paracoccidioidomycosis (PCM) is a systemic mycosis endemic in Latin America, with a high prevalence in Brazil, Argentina, Colombia and Venezuela. The aetiologic agent of disease is a thermal dimorphic fungus, Paracoccidioides ...
-
Expression of GP82 and GP90 surface glycoprotein genes of Trypanosoma cruzi during in vivo metacyclogenesis in the insect vector Rhodnius prolixus
(Elsevier B.V., 2008-01-01)Trypanosoma cruzi, the parasite causing Chagas' disease, relies on triatomines for its transmission. T cruzi metacyclic trypomastigotes express GP82 and GP90, which are developmentally regulated surface proteins that have ...
-
Glycosphingolipid antigens from Leishmania (L) amazonensis amastigotes. Binding of anti-glycosphingolipid monoclonal antibodies in vitro and in vivo
(Assoc Bras Divulg Cientifica, 1997-03-01)Specific glycosphingolipid antigens of Leishmania (L.) amazonensis amastigotes reactive with the monoclonal antibodies (MoAbs) ST-3, ST-4 and ST-5 were isolated, and their structure was partially elucidated by negative ion ...
-
Immunochemical and subcellular localization of the 43 kDa glycoprotein antigen of Paracoccidioides brasiliensis with monoclonal antibodies
(Blackwell Science Ltd, 1996-06-01)Two monoclonal antibodies ST-7 (IgG1) and ST-8 (IgG2b), directed against a 43 kDa glycoprotein (gp43) of Paracoccidioides brasiliensis were produced. It was possible to detect the gp43 by ELISA in amounts as low as 100 ng ...
-
Interaction between Shiga Toxin and Monoclonal Antibodies: Binding Characteristics and in Vitro Neutralizing Abilities
(Mdpi Ag, 2012-09-01)Monoclonal antibodies (MAbs) have been employed either for diagnosis or treatment of infections caused by different pathogens. Specifically for Shiga toxin-producing Escherichia coli (STEC), numerous immunoassays have been ...
-
Monoclonal antibodies to identify Tomato mosaic tobamovirus (ToMV)
(Sociedade Brasileira de Microbiologia, 2001-10-01)Monoclonal antibodies were obtained against Tomato mosaic tobamovirus (ToMV) isolated in Brazil. One antibody (8G7G2) isotyped as IgG2b (kappa light chain) showed strong specificity and very low cross reaction with the ...
-
A surface 75-kDa protein with acid phosphatase activity recognized by monoclonal antibodies that inhibit Paracoccidioides brasiliensis growth
(Elsevier B.V., 2007-10-01)Paracoccidioides brasiliensis is a thermo-dimorphic fungus responsible for paracoccidioidomycosis (PCM), a systemic granulomatous mycosis prevalent in Latin America. the fungus releases many antigens which may be transiently ...
